New generation super alloy candidates for medical applications: Corrosion behavior, cation release and biological evaluation

Reclaru, Lucien; Ziegenhagen, René; Unger, Ronald E.; Eschler, P.-Y.; Constantin, Floriana

doi:10.1016/j.msec.2014.09.027

Cited by 6 publications

(6 citation statements)

References 7 publications

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“…As far as extraction is concerned, a mixture of cations in relatively high concentrations was noted, and, therefore, a cocktail effect was not excluded. The results obtained in the biological assays WST-1 and TNF-alpha were in correlation with the corrosion and extraction evaluation [2]. The encouraging results of this study may support the development of superalloys for medical applications.…”

Section: Introductionsupporting

confidence: 70%

“…However, superalloys for dental use are not yet available, and only few studies concerning the new generation of superalloy candidates for medical applications have recently been developed. Three superalloy candidates [2] for medical application were assessed by means of corrosion behavior, cation release, and biological evaluation for a prolonged contact with skin, in comparison with two reference austenitic stainless steels 316L and 904L. The three superalloy candidates assessed were X1 CrNiMoMnW 24-22-6-3-2 N, NiCr21 MoNbFe 8-3-5 AlTi, and CoNiCr 35-20 Mo 10 BTi.…”

Section: Introductionmentioning

confidence: 99%

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Assessment of Dental Alloys by Different Methods

Ardelean¹,

Reclaru²,

Borţun³

et al. 2015

Superalloys

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Abstract"lloys are used in various areas of dentistry. The field of dental alloys is a very extensive one, encompassing both the materials themselves as well as the manufacturing methods, which are constantly developing. Our chapter focuses on corrosion and biocompatibility assessment, using various methods. "t present there is no perfect dental alloy. Superalloys for dental use are not yet available, and only few studies concerning the new generation of superalloy candidates for medical applications have recently been developed, with promising results.

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Section: Introductionsupporting

confidence: 70%

Section: Introductionmentioning

confidence: 99%

Assessment of Dental Alloys by Different Methods

Ardelean¹,

Reclaru²,

Borţun³

et al. 2015

Superalloys

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“…The corrosion behavior evaluation of the alloys was carried out based on techniques specific to the type of corrosion considered [28,29]:electrochemical evaluation of the generalized corrosion by the technique of the rotating electrode [30] and taking into account, for evaluation, the American Society for Testing and Materials ASTM G3-89 [31] and ASTM G59-97 [32] standards;pitting and crevice corrosion according to the ASTM F746-04 [33] standard;galvanic corrosion [34] taking into account the mixed potential theory [35]. …”

Section: Methodsmentioning

confidence: 99%

“…electrochemical evaluation of the generalized corrosion by the technique of the rotating electrode [30] and taking into account, for evaluation, the American Society for Testing and Materials ASTM G3-89 [31] and ASTM G59-97 [32] standards;…”

Section: Methodsmentioning

confidence: 99%

Corrosion Resistance of Stainless Steels Intended to Come into Direct or Prolonged Contact with the Skin

Ziegenhagen¹,

Reclaru

Ardelean

et al. 2019

Materials

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The biocompatibility of materials in contact with a living tissue becomes a puzzle in the overall picture of assessing the toxic effects of chemicals that come into contact with us. Allergic reactions to substances are a significant and growing health problem affecting large parts of the population in Europe. Wristwatches are objects worn in prolonged contact with the skin, being subject to localized corrosion, especially pitting and crevice types, in sulfide-chloride medium, and high wear in the bracelets joints. Watches of medium quality are usually made of stainless steels. The X2 CrNiMo 17-12-2 316L grade as well as X1 CrNiMo 20-25-5 Cu 1 or 904L are commonly used, having good resistance to generalized corrosion. The passive layer is nevertheless insufficient to ensure complete immunity in all cases of localized corrosion encountered during wear. For this reason, a high-corrosion-resistant steel: X1 CrNiMo 18-15-4 N 0.15 or 317LMN, from three different suppliers was evaluated. Metallographic characterization was carried out. The corrosion behavior evaluation was performed for the generalized corrosion, pitting and crevice corrosion and galvanic corrosion. Galvanic couples steel 317LMN-gold 18K alloy 3N and gold 18K 5M were used. The results of the generalized and pitting corrosion test indicated three basic groups. All of the 317LMNs were similar. The 316L variants tested noticeably worse. The 904Ls were difficult to discern, but certainly easier than the 316Ls and, possibly, at least comparable to the 317LMNs.

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“…NiCr alloys are widely used in dental skeletal structures and orthopedic implants such as screws, pins, plates, crowns, bridge castings, inlays and denture bases [1][2][3][4]. Cr is the main alloying element facilitating a good corrosion performance due to the formation of a stable passive oxide layer [5][6][7]. The main concern regarding the use of NiCr alloys is the release of allergenic and toxic Ni 2+ ions into the human body [8][9][10][11][12].…”

Section: Introductionmentioning

confidence: 99%

Electrochemical Synthesis of Polypyrrole and Polypyrrole-Indomethacin Coatings on NiCr Alloys Involving Deep Eutectic Solvents

Golgovici

Cârlan

Popescu

et al. 2020

Metals

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There is an increased interest in the use of the deep eutectic solvents (DESs) as electrolytic media for electrochemical synthesis of conducting polymers, which could influence their characteristics. Moreover, the polypyrrole layers represent an attractive route for pharmaceutical drug release. The paper presents several experimental results regarding the electrodeposition of polypyrrole and of polypyrrole-indomethacin coatings on nickel-chromium NiCr alloy substrates widely used in dentistry, involving DES-based electrolytes, namely eutectic mixtures of choline chloride and malonic acid. This type of electrolyte also allowed an enhanced dissolution of indomethacin as compared to aqueous ones. The electropolymerization process has been investigated by cyclic voltammetry and chronoamperometry. The obtained indomethacin containing polymeric coatings have been thoroughly characterized involving scanning electron microscopy (SEM), Fourier transform infrared (FTIR) spectroscopy, contact angle measurements in simulated body fluid (SBF) and indomethacin release studies. Adherent and uniform polypyrrole-indomethacin layers have been obtained on NiCr alloy substrates. The release tests showed that the polypyrrole coatings containing indomethacin may deliver the drug molecules for longer periods of at least 17 days. The maximum released amount was around 99.6% suggesting these layers may act as an active reservoir for indomethacin. Kinetics analysis based on the Korsmeyer–Peppas model suggested the diffusion of the drug out of the polymer layer as the most probable mechanism governing the release.

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New generation super alloy candidates for medical applications: Corrosion behavior, cation release and biological evaluation

Cited by 6 publications

References 7 publications

Assessment of Dental Alloys by Different Methods

Assessment of Dental Alloys by Different Methods

Corrosion Resistance of Stainless Steels Intended to Come into Direct or Prolonged Contact with the Skin

Electrochemical Synthesis of Polypyrrole and Polypyrrole-Indomethacin Coatings on NiCr Alloys Involving Deep Eutectic Solvents

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