New glucosamine Schiff base grafted poly(acrylic acid) as efficient Cu2+ ions adsorbent and antimicrobial agent

Shandil, Yashwant; Dautoo, Umesh K.; Chauhan, Ghanshyam S.

doi:10.1016/j.jece.2018.09.011

Cited by 6 publications

(6 citation statements)

References 53 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The v (CC) band of the aromatic nucleus is observed at 1573 cm −1 58 . In both complexes' spectra, the IR chart reveals a vibration at 1095 cm −1 that has been attributed to v (CO) enolic 56 . Some bands have appeared between 2854 and 1543 cm −1 in both complexes, these bands may be described the v (CH), and v (CC) stretching of the benzene ring environment 59 .…”

Section: Resultsmentioning

confidence: 89%

“…The 3417 cm −1 absorbing band can be interpreted as the v (OH) stretching bands associated with the benzene ring moiety 52,55 . The band also corresponds to the OH stretching of the hydroxyl groups of glucosamine moieties as mentioned in further glucosamine investigations 52,56 . Additionally, the v (COH) stretching bands of d ‐glucosamine are typically found around 1268, 1219, 1165, and 1151 cm −1 52,57 .…”

Section: Resultsmentioning

confidence: 93%

“…58 In both complexes' spectra, the IR chart reveals a vibration at 1095 cm À1 that has been attributed to v(C O) enolic. 56 Some bands have appeared between 2854 and 1543 cm À1 in both complexes, these bands may be described the v (C H), and v(C C) stretching of the benzene ring environment. 59 The absorption bands at 972 cm À1 in the vanadyl complex have been observed, and these bands can be attributed to the v(V O) vibration.…”

Section: Structural Characterizationmentioning

confidence: 95%

“…24 For Sn (ph) 2 (HL) 2 complex, the broad bands observed at around 3286 cm À1 correspond to the O H stretching of the hydroxyl groups present in glucosamine moieties. 56 Also, the IR spectrum displays the appearance of new bands at 554 and 473 cm À1 . This indicates the coordination of the azomethine nitrogen and the (OH) salicylaldehyde moiety of the ligand with Sn (ph) 2 (IV) ion after its deprotonation.…”

Section: Structural Characterizationmentioning

confidence: 97%

“…52,55 The band also corresponds to the O H stretching of the hydroxyl groups of glucosamine moieties as mentioned in further glucosamine investigations. 52,56 Additionally, the v(C OH) stretching bands of D-glucosamine are typically found around 1268, 1219, 1165, and 1151 cm À1 . 52,57 The v(C C) band of the aromatic nucleus is observed at 1573 cm À1 .…”

Section: Structural Characterizationmentioning

confidence: 99%

See 4 more Smart Citations

Synthesis, anticancer, anti‐inflammatory, antimicrobial activities, molecular docking, and Density functional theory studies of nanometal (IV) glycoconjugates

Al Motwaa,

Al‐Otaibi,

Abubakr

et al. 2024

Applied Organom Chemis

View full text Add to dashboard Cite

Oxovanadium (IV) and diphenyltin (IV) complexes were synthesized on the nanoscale based on the Schiff base (H2L) derived from salicylaldehyde and d‐glucosamine. The complexes were formed with a molar ratio of 1:1 and 1:2 (metal: dligand) relative to oxovanadium (IV) and diphenyltin (IV), respectively. Fourier‐transform infrared spectroscopy, 1H and 13C nuclear magnetic resonance, mass fragmentations, electronic transitions, thermogravimetric analysis, and density functional theory were employed to validate the structure of synthesized compounds. The results demonstrated that the ligand (H2L) was successfully attached to oxovanadium (IV) and diphenyltin (IV) as di‐anionic and mono‐anionic ligands, respectively. The size of the complexes was investigated using the transmission scanning microscope. The work presents a prospective concept for the drug design of the targeted anticancer through the glucose moiety. All compounds revealed remarkable anticancer activities against the colorectal (HCT‐116) cell line, recording IC50 values 4.94, 21.73, and 62.5 μg/ml for VO (II)(L), free H2L, and Sn (ph)2(HL)2, respectively. The IC50 value of VO (II)(L) complex was increased after the quercetin inhibitor. Therefore, the sugar‐conjugated compound can be recognized by the glucose recognition binding site of GLUT and their cell‐killing effect depends highly on the GLUT inhibitor, quercetin. The potential GLUT transportability of the compounds was investigated through a molecular docking study. The anti‐migration activity was investigated for VO (II)(L) complex. The free ligand observed the best antimicrobial results. The antibacterial stimulation was investigated and represented different interaction types with the selected ribosyl transferase enzyme.

show abstract

Section: Resultsmentioning

confidence: 89%