New goals for depression therapy

Петрова, Н. Н.

doi:10.17116/jnevro202212211157

Z. nevrol. psikhiatr. im. S.S. Korsakova

2022

DOI: 10.17116/jnevro202212211157

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New goals for depression therapy

Н. Н. Петрова¹

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2024

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Cited by 2 publications

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Diagnosis and treatment of depression according to the functional recovery paradigm

Usov

2023

RJTAO

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Since the appearance of the first antidepressants, ideas about the goals of long-term treatment of depression have changed considerably. The prevailing priority in the 1960s to 1980s of relieving current depressive symptoms and ending the current episode – shifted to achieving remission in the early 1990s and functional recovery in the mid-2010s. The general recognition of a new approach to the treatment of depression is reflected in the inclusion of functional disorder in the ICD-11 diagnostic criteria for a depressive episode. The paradigm shift in therapy has been driven by advances in the field of psychopharmacology that have led to the development of antidepressants with a fundamentally new mechanism of action that provides a broader therapeutic effect combined with a more favorable tolerability profile. Agomelatine provides a harmonious and complete reduction of depression symptoms, including those resistant to other antidepressants, and a stable clinical and functional remission of high quality, i.e., it allows the achievement of all three therapeutic goals.

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Diagnosis and treatment of depression according to the functional recovery paradigm

Usov

2023

RJTAO

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Antidepressants in psychiatric practice

Abritalin,

Khabarov

2024

S.S. Korsakov J. Neuro. Psych.

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New goals for depression therapy

Cited by 2 publications

References 39 publications

Diagnosis and treatment of depression according to the functional recovery paradigm

Diagnosis and treatment of depression according to the functional recovery paradigm

Antidepressants in psychiatric practice

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