New Heart Failure After Myocardial Infarction (From the National Cardiovascular Data Registries [NCDR] Linked With All-Payer Claims)

Faridi, Kamil F.; Bhalla, Narinder; Atreja, Nipun; Venditto, John; Khan, Naeem; Wilson, Thomas E.; Fonseca, Eileen; Shen, Changyu; Yeh, Robert W.; Secemsky, Eric A.

doi:10.1016/j.amjcard.2021.04.019

Cited by 10 publications

(5 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the present study, 86% of patients without COVID-19 with out-of-hospital STEMI underwent coronary angiography, compared with 96% of patients with STEMI in the American College of Cardiology’s Chest Pain–MI Registry, a disease-specific clinical database that manually collects and audits data on consecutive MI patients at nearly 800 US hospitals . Similarly, in the study by Saad et al, 30.4% of patients without COVID-19 with STEMI developed acute heart failure during hospitalization and 17.3% developed cardiogenic shock, both of which are considerably higher than the rates observed in contemporary, audited, multicenter US registries . Fundamentally, administrative coding schema designed primarily for billing cannot be guaranteed to provide an accurate portrait of a clinical entity, either at the individual or population level.…”

mentioning

confidence: 49%

“…6 Similarly, in the study by Saad et al, 30.4% of patients without COVID-19 with STEMI developed acute heart failure during hospitalization and 17.3% developed cardiogenic shock, 5 both of which are considerably higher than the rates observed in contemporary, audited, multicenter US registries. 7,8 Fundamentally, administrative coding schema designed primarily for billing cannot be guaranteed to provide an accurate portrait of a clinical entity, either at the individual or population level.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Myocardial Infarction During the COVID-19 Pandemic

Fanaroff

García

Giri

2021

JAMA

View full text Add to dashboard Cite

Early during the COVID-19 pandemic, it was recognized that infection with SARS-CoV-2 was associated with an increased risk of both arterial and venous thrombotic complications. This association is strongest for venous thromboembolic disease, but the risk of myocardial infarction (MI) is approximately doubled in the 7 days after COVID-19 diagnosis. 1 Multiple studies have suggested worse outcomes in patients with COVID-19 and MI, 2,3 with direct effects of the virus on endothelial cells, increased propensity for vascular thrombosis, and deficient care delivery all mechanistically implicated. 4 The study by Saad et al 5 in this issue of JAMA reexamines these findings in the largest cohort yet described. Using the Vizient Clinical Database, an administrative database of more than 700 US academic hospitals and affiliates, the authors described in-hospital outcomes for patients with COVID-19 and ST-segment elevation MI (STEMI). Propensity score matching was used to compare patients with COVID-19 and STEMI with 2 separate control groups: patients without COVID-19 hospitalized with STEMI in 2020 and patients hospitalized with STEMI in 2019 before the onset of the pandemic. By comparing patients who were cared for under the same system constraints, the first comparison attempted to isolate the association between concomitant COVID-19 and STEMI outcomes, whereas the second comparison evaluated the association of both COVID-19 infection and care delivery before and after the COVID-19 pandemic with STEMI outcomes.The authors found that among 36 309 patients with outof-hospital STEMI admitted to more than 500 primary percutaneous coronary intervention (PCI)-capable hospitals in 2020, a total of 565 had concomitant COVID-19; 359 of 1937 patients with in-hospital STEMI had concomitant COVID-19. After adjusting for patient and hospital factors in the propensity score-matched analysis, 15% of patients with COVID-19 and out-of-hospital STEMI died compared with 11% of patients without COVID-19 with STEMI (odds ratio, 1.43 [95% CI, 1.10-1.86]); 77% of patients with COVID-19 and in-hospital STEMI died compared with 44% of patients without 4.11 [95% CI,). These results were similar when comparing patients with COVID-19 and STEMI vs patients without COVID-19 and STEMI from 2020 or patients with STEMI from 2019 in the pre-COVID-19 era.The study by Saad et al 5 represents an important effort to better describe MI outcomes during the pandemic, although several limitations challenge the interpretation of these data. First, the administrative database used in this study lacks granular clinical information. Although the

show abstract

mentioning

confidence: 49%

mentioning

confidence: 99%

Myocardial Infarction During the COVID-19 Pandemic

Fanaroff

García

Giri

2021

JAMA

View full text Add to dashboard Cite

show abstract

“…In this prospective of older Vietnamese patients with MI, we found a 12.8% incidence of post-MI HFrEF 3 months after hospital discharge. Previous studies have reported an incidence of post-MI HF ranging from 11-50%, although with different post-MI HF de nitions and without ejection fraction classi cation [1,[14][15][16][18][19][20][21]. Notably, in older populations, Ezekowitz et al reported a 46% incidence of post-MI HF after 1 year, whereas Kochar et al reported a 10% incidence [14,15].…”

Section: Discussionmentioning

confidence: 99%

“…However, most previous studies on the incidence of post-MI HF were conducted decades ago with retrospective designs and registry data with International Classi cation of Diseases (ICD) code-de ned HF, leading to heterogeneous post-MI HF de nitions across studies (new diagnosis of HF and/or HF rehospitalisation based on the ICD codes) [1,[14][15][16][17][18][19][20][21]. Furthermore, these studies did not focus on older populations or ejection fraction classi cations.…”

Section: Introductionmentioning

confidence: 99%

Post-myocardial infarction heart failure with reduced ejection fraction in older patients: a prospective multicentre study in Vietnam

Phan,

Nguyen,

et al. 2023

Preprint

View full text Add to dashboard Cite

Background Heart failure (HF) is a common complication of myocardial infarction (MI) in older adults. However, data on the incidence of and risk factors for post-MI HF with reduced ejection fraction (HFrEF) are limited, especially among older Asian populations. Therefore, in this study, we aimed to determine the incidence of and risk factors for post-MI HFrEF in older Vietnamese patients with MI. Methods This prospective multicentre study enrolled 234 patients aged ≥ 60 years hospitalised for MI without prior HF at two tertiary hospitals in Vietnam. Data on demographics, MI details, treatments, and echocardiographic left ventricular ejection fraction (LVEF) during hospitalisation were collected. Post-MI HFrEF was defined as the diagnosis of HFrEF according to European Society of Cardiology guideline criteria at follow-up 3 months post-discharge. Multivariate logistic regression analysis identified the factors associated with post-MI HFrEF. Results Thirty patients (12.8%) developed post-MI HFrEF. Notably, most patients (94%) underwent coronary angiography, whereas 92% underwent revascularisation during the index hospitalisation. Independent predictors were female sex (odds ratio [OR]: 4.09, 95% confidence interval [CI]: 1.43–12.89), highest troponin T levels (OR: 1.15 per 1000 ng/L increase, 95% CI: 1.03–1.30), and reduced LVEF at discharge (OR: 6.88, 95% CI: 2.37–22.06). Conclusions In this study, with a high rate of coronary revascularisation, the incidence of post-MI HFrEF was 12.8% at 3 months. Female sex, larger infarct size reflected by higher peak troponin T levels, and lower pre-discharge LVEF were associated with increased HFrEF risk. These findings can guide post-MI monitoring and early therapy in high-risk individuals to optimise outcomes.

show abstract

“…It is known that sympathetic hyperactivation often occurs during the recovery period after AMI [ 3 ] and is a key factor of cardiac and electronic remodeling post AMI [ 4 , 5 ]. According to literature, under the premise of standardized treatment after AMI, the incidence of heart failure within 1 year is about 8%, and the incidence of heart failure within 5 years is about 20% post AMI [ 6 ]. Ventricular arrhythmias, including ventricular fibrillation, ventricular tachycardia, and ventricular premature beats, are common arrhythmias after AMI.…”

Section: Introductionmentioning

confidence: 99%

Effects of renal denervation on cardiac function after percutaneous coronary intervention in patients with acute myocardial infarction

Gao¹,

Xu²,

Ye³

et al. 2023

Heliyon

View full text Add to dashboard Cite

New Heart Failure After Myocardial Infarction (From the National Cardiovascular Data Registries [NCDR] Linked With All-Payer Claims)

Cited by 10 publications

References 27 publications

Myocardial Infarction During the COVID-19 Pandemic

Myocardial Infarction During the COVID-19 Pandemic

Post-myocardial infarction heart failure with reduced ejection fraction in older patients: a prospective multicentre study in Vietnam

Effects of renal denervation on cardiac function after percutaneous coronary intervention in patients with acute myocardial infarction

Contact Info

Product

Resources

About