1989
DOI: 10.1055/s-2006-961822
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New Hepatoprotective Triterpenes formCanarium album

Abstract: Canarium album has yielded seven triterpenes of which two appear to be novel. The new triterpenes, which were identified on the basis of spectral characteristics, are urs-12-ene-3 alpha, 16 beta-diol and olean-12-ene-3 alpha, 16 beta-diol. Both compounds exhibited hepatoprotective activity in primary cultured rat hepatocytes intoxicated with D-galactosamine.

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Cited by 53 publications
(27 citation statements)
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“…α-Amyrin, β-amyrin, 3-epi-α-amyrin, 3-epi-β-amyrin, urs-12-ene-3α,16β-diol, olean-12-ene-3α,16β diol, and oeanlic acid are representative components of triterpenes and possess heptoprotective function. α-Cubenene, α-copaene, β-cubebene, (E)-β-caryophyllene, α-humelene, germacrene D, and spathulenol are representative components of sesquiterpenes [7,8].…”
Section: Terpenesmentioning
confidence: 99%
See 1 more Smart Citation
“…α-Amyrin, β-amyrin, 3-epi-α-amyrin, 3-epi-β-amyrin, urs-12-ene-3α,16β-diol, olean-12-ene-3α,16β diol, and oeanlic acid are representative components of triterpenes and possess heptoprotective function. α-Cubenene, α-copaene, β-cubebene, (E)-β-caryophyllene, α-humelene, germacrene D, and spathulenol are representative components of sesquiterpenes [7,8].…”
Section: Terpenesmentioning
confidence: 99%
“…Three coumarins scoparone (7), scopoletin (8), and (E)-3, 3′-dihydroxy-4, 4′-dimethoxystilbene were isolated from Qingguo [1].…”
Section: Coumarinsmentioning
confidence: 99%
“…Moreover, they are believed to exhibit antioxidant effects in vitro and in vivo (Tamai et al, 1989;Ito et al, 1990;Wang et al, 2010). The dried fruits are also reported to have anti-viral, anti-bacterial, anti-inflammatory, and detoxifying effects (Zhang and Lin, 2008).…”
Section: Introductionmentioning
confidence: 99%
“…The EIMS of the compound (7) showed the molecular ion peak at m/z 426.2000, corresponding to the molecular formula C 30 H 50 O indicating six degrees of un-saturation in the molecule. The mass spectrum of the compound (7) showed characteristic fragmentation pattern of amyrin skeleton with double bond at C-12 [22].…”
mentioning
confidence: 99%