New Heterogeneous Nano-Catalyst: Synthesis and Catalytic Effect on the Green Synthesis of 1-Substituted and 5-Substituted 1H-Tetrazole Derivatives

Abstract

A novel heterogeneous catalyst containing Schiff base coordinated Cu(II) covalently attached to Fe3O4@SiO2 nanoparticles through imidazolium linker [Fe3O4@SiO2-Im(Br)-SB-Cu (II)] was synthesized and characterized by using various techniques. The catalytic efficiency of this nano-catalyst was tested in the synthesis of tetrazole derivatives. The investigation revealed that i) The catalyst is very efficient in the synthesis of tetrazole derivatives with high yield (97%) in aqueous medium; ii) The catalytic effectiveness is due the synergy between the metallic center and the imidazolium ion and iii) The reuse advantage of the catalyst without contamination or significant loss (12% of loss range) in the catalytic activity.