New insight into copy number variations of goat SMAD2 gene and their associations with litter size and semen quality

Wijayanti, Dwi; Luo, Yunyun; Bai, Yangyang; Pan, Chuanying; Liu, Qu; Guo, Zhang; Lan, Xianyong

doi:10.1016/j.theriogenology.2023.05.012

Cited by 2 publications

(1 citation statement)

References 34 publications

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“…Notably, recent research endeavors have delved into the investigation of the association between CNV in specific genes and a variety of phenotypic traits in animals, including growth characteristics in cattle ( 27 , 28 ), goats ( 29 – 31 ), sheep ( 32 ) and horses ( 33 – 38 ). These studies have also extended their focus to examine the link between CNVs and other vital phenotypes, such as reproduction traits ( 39 , 40 ) and disease resistance ( 7 , 41 ). These studies have unveiled CNV as a key player linked to diverse facets of phenotypic diversity and economic traits in animal realms.…”

Section: Introductionmentioning

confidence: 99%

Advancements in copy number variation screening in herbivorous livestock genomes and their association with phenotypic traits

Liu,

Chen,

Huang

et al. 2024

Front. Vet. Sci.

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Copy number variations (CNVs) have garnered increasing attention within the realm of genetics due to their prevalence in human, animal, and plant genomes. These structural genetic variations have demonstrated associations with a broad spectrum of phenotypic diversity, economic traits, environmental adaptations, epidemics, and other essential aspects of both plants and animals. Furthermore, CNVs exhibit extensive sequence variability and encompass a wide array of genomes. The advancement and maturity of microarray and sequencing technologies have catalyzed a surge in research endeavors pertaining to CNVs. This is particularly prominent in the context of livestock breeding, where molecular markers have gained prominence as a valuable tool in comparison to traditional breeding methods. In light of these developments, a contemporary and comprehensive review of existing studies on CNVs becomes imperative. This review serves the purpose of providing a brief elucidation of the fundamental concepts underlying CNVs, their mutational mechanisms, and the diverse array of detection methods employed to identify these structural variations within genomes. Furthermore, it seeks to systematically analyze the recent advancements and findings within the field of CNV research, specifically within the genomes of herbivorous livestock species, including cattle, sheep, horses, and donkeys. The review also highlighted the role of CNVs in shaping various phenotypic traits including growth traits, reproductive traits, pigmentation and disease resistance etc., in herbivorous livestock. The main goal of this review is to furnish readers with an up-to-date compilation of knowledge regarding CNVs in herbivorous livestock genomes. By integrating the latest research findings and insights, it is anticipated that this review will not only offer pertinent information but also stimulate future investigations into the realm of CNVs in livestock. In doing so, it endeavors to contribute to the enhancement of breeding strategies, genomic selection, and the overall improvement of herbivorous livestock production and resistance to diseases.

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Section: Introductionmentioning

confidence: 99%

Advancements in copy number variation screening in herbivorous livestock genomes and their association with phenotypic traits

Liu,

Chen,

Huang

et al. 2024

Front. Vet. Sci.

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Determinant genetic markers of semen quality in livestock

Khan,

Chen,

Naz

et al. 2024

Front. Endocrinol.

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The reproductive efficiency of livestock is crucial for agricultural productivity and economic sustainability. One critical factor in successful fertilization and the viability of offspring is the quality of semen. Poor semen quality, especially in frozen-thawed semen used in artificial insemination (AI) have been shown to influence conception outcomes, resulting a negative impact on livestock production. Recent advancements in genetic research have identified specific markers linked to semen quality traits in various livestock species, such as cattle, sheep, goats, pigs, buffalo, and equines. These genetic markers are essential in screening males for breeding suitability, which in turn enhances selective breeding programs. Understanding these markers is crucial for improving reproductive performance and increasing productivity in livestock populations. This review offers a comprehensive overview of the genetic markers associated with semen quality in key livestock. It explores the underlying genetic mechanisms and their practical implications in animal breeding and management. The review underscores the importance of integrating genetic insights into breeding strategies to optimize reproductive efficiency and ensure the sustainable development of livestock industries.

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New insight into copy number variations of goat SMAD2 gene and their associations with litter size and semen quality

Cited by 2 publications

References 34 publications

Advancements in copy number variation screening in herbivorous livestock genomes and their association with phenotypic traits

Advancements in copy number variation screening in herbivorous livestock genomes and their association with phenotypic traits

Determinant genetic markers of semen quality in livestock

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