New insights and discoveries in anion receptor chemistry

McNaughton, Daniel A.; Ryder, William G.; Gilchrist, Alexander M.; Wang, Patrick; Fares, Mohamed; Wu, Xin; Gale, Philip A.

doi:10.1016/j.chempr.2023.07.006

“…In the field of supramolecular anion recognition chemistry, [1][2][3] the use of OÀ H hydrogen bonding groups as recognition motifs has lagged behind the use of NÀ H [1,2,4,5] and CÀ H hydrogen bond donors, [6] and halogen [7][8][9] and chalcogen bonding. [8,9] This is perhaps surprising given the ease with which OÀ H groups can be synthesised and their potent hydrogen bonding strength.…”

Section: Introductionmentioning

confidence: 99%

A Cationic Catechol Derivative Binds Anions in Competitive Aqueous Media

Goodwin,

White

2024

Chemistry An Asian Journal

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A simple dihydroxy isoquinolinium molecule (3+) was prepared by a modification of a literature procedure. Interestingly, during optimisation of the synthesis a small amount of the natural product pseudopalmatine was isolated, and characterised for the first time by X‐ray crystallography. Compound 3+ contains a catechol motif and positive charge on the same scaffold and was found to be a potent anion receptor, binding sulfate strongly in 8 : 2 d6‐acetone:D2O and 7 : 3 d6‐acetone:D2O (Ka>104 and 2,100 M−1, respectively). Unsurprisingly, chloride binding was much weaker, even in the less polar solvent mixture 9 : 1 d6‐acetone:D2O. The sulfate binding is remarkably strong for such a simple molecule, however anion binding studies were complicated by the tendency of the molecule to react with BPh4− or BF4− species during anion metathesis reactions. This gave two unusual zwitterions containing tetrahedral boronate centres, which were both characterised by X‐ray crystallography.

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Challenges and Applications of Supramolecular Metalate Chemistry

O'Connell‐Danes,

Ngwenya,

Morrison

et al. 2024

Angewandte Chemie

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While the supramolecular chemistry of simple anions is ubiquitous, the targeting and exploitation of their metal‐containing relatives, the metalates, is less well understood. This mini review highlights the latest advances in this emergent area by discussing the supramolecular chemistry of metalates thematically, with a focus on the exploitation of metalates in a diversity of applications, including medical imaging and therapy, environmental remediation, molecular magnetism, catalysis, perovskite materials, and metal separations. The unifying features of these systems are identified with a view to allow the supramolecular chemist to target the unique material properties of the metalates, even in areas that are currently relatively immature.

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Challenges and Applications of Supramolecular Metalate Chemistry

O'Connell‐Danes,

Ngwenya,

Morrison

et al. 2024

Angew Chem Int Ed

0

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While the supramolecular chemistry of simple anions is ubiquitous, the targeting and exploitation of their metal‐containing relatives, the metalates, is less well understood. This mini review highlights the latest advances in this emergent area by discussing the supramolecular chemistry of metalates thematically, with a focus on the exploitation of metalates in a diversity of applications, including medical imaging and therapy, environmental remediation, molecular magnetism, catalysis, perovskite materials, and metal separations. The unifying features of these systems are identified with a view to allow the supramolecular chemist to target the unique material properties of the metalates, even in areas that are currently relatively immature.

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New insights and discoveries in anion receptor chemistry

Cited by 15 publications

References 80 publications

A Cationic Catechol Derivative Binds Anions in Competitive Aqueous Media

A Cationic Catechol Derivative Binds Anions in Competitive Aqueous Media

Challenges and Applications of Supramolecular Metalate Chemistry

Challenges and Applications of Supramolecular Metalate Chemistry

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