New insights in aptamer-targeted nanoliposomes for the treatment of breast cancer

Jain Singhai, Nidhi; Maheshwari, Rahul; Khatri, Kapil

doi:10.1016/j.jddst.2023.104880

Cited by 5 publications

(1 citation statement)

References 108 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Passive targeting mechanisms, based on the enhanced permeation and retention (EPR) effect for liposomal drug delivery, showed undesirable systemic side effects and suboptimal antitumor effectiveness [55]. The potential enhancement is conceivable through the utilization of delivery vehicles such as aptamers possessing active tumortargeting capabilities [56,57].…”

Section: Aptamer Conjugation With Organic Materials 241 Aptamer-lipos...mentioning

confidence: 99%

Aptamer-Based Smart Targeting and Spatial Trigger–Response Drug-Delivery Systems for Anticancer Therapy

Park,

Lee,

Park

2024

Biomedicines

View full text Add to dashboard Cite

In recent years, the field of drug delivery has witnessed remarkable progress, driven by the quest for more effective and precise therapeutic interventions. Among the myriad strategies employed, the integration of aptamers as targeting moieties and stimuli-responsive systems has emerged as a promising avenue, particularly in the context of anticancer therapy. This review explores cutting-edge advancements in targeted drug-delivery systems, focusing on the integration of aptamers and stimuli-responsive platforms for enhanced spatial anticancer therapy. In the aptamer-based drug-delivery systems, we delve into the versatile applications of aptamers, examining their conjugation with gold, silica, and carbon materials. The synergistic interplay between aptamers and these materials is discussed, emphasizing their potential in achieving precise and targeted drug delivery. Additionally, we explore stimuli-responsive drug-delivery systems with an emphasis on spatial anticancer therapy. Tumor microenvironment-responsive nanoparticles are elucidated, and their capacity to exploit the dynamic conditions within cancerous tissues for controlled drug release is detailed. External stimuli-responsive strategies, including ultrasound-mediated, photo-responsive, and magnetic-guided drug-delivery systems, are examined for their role in achieving synergistic anticancer effects. This review integrates diverse approaches in the quest for precision medicine, showcasing the potential of aptamers and stimuli-responsive systems to revolutionize drug-delivery strategies for enhanced anticancer therapy.

show abstract

Section: Aptamer Conjugation With Organic Materials 241 Aptamer-lipos...mentioning

confidence: 99%

Aptamer-Based Smart Targeting and Spatial Trigger–Response Drug-Delivery Systems for Anticancer Therapy

Park,

Lee,

Park

2024

Biomedicines

View full text Add to dashboard Cite

show abstract

Niosomes based formulation containing tenoxicam: A newer solution for the rheumatic diseases

Maheshwari,

Sharma,

Chidrawar

2024

Annales Pharmaceutiques Françaises

View full text Add to dashboard Cite

Development of engineered transferosomal gel containing meloxicam for the treatment of osteoarthritis

Maheshwari,

Sharma,

Chidrawar

2024

Annales Pharmaceutiques Françaises

View full text Add to dashboard Cite

New insights in aptamer-targeted nanoliposomes for the treatment of breast cancer

Cited by 5 publications

References 108 publications

Aptamer-Based Smart Targeting and Spatial Trigger–Response Drug-Delivery Systems for Anticancer Therapy

Aptamer-Based Smart Targeting and Spatial Trigger–Response Drug-Delivery Systems for Anticancer Therapy

Niosomes based formulation containing tenoxicam: A newer solution for the rheumatic diseases

Development of engineered transferosomal gel containing meloxicam for the treatment of osteoarthritis

Contact Info

Product

Resources

About