New Insights Into the Comorbidity of Coronary Heart Disease and Depression

Wu, Yeshun; Zhu, Bin; Chen, Zijun; Duan, Jiahao; Luo, Ailin; Yang, Ling; Yang, Chun

doi:10.1016/j.cpcardiol.2019.03.002

Cited by 47 publications

(36 citation statements)

References 159 publications

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“…Furthermore, although the differences did not show a statistical significance, higher incidence of diabetes mellitus and higher Gensini scores were noted in the depressive group (both mild and moderate/severe groups), indicating that diabetes mellitus might be related to the occurrence of SCAD accompanied by depressive symptoms, and depressive symptoms could aggravate the degree of coronary artery stenosis. Given that these are all involved in inflammation, metabolism disorder, endothelial dysfunction, and platelet activation [5, 6, 33], a complex pathogenic network might likely exist in SCAD, diabetes mellitus, and depressive symptoms. Moreover, after searching the literature from January 1946 to December 2014, Doi-Kanno et al showed that diabetes mellitus was a possible risk factor for depression in patients with myocardial infarction who underwent PCI [34].…”

Section: Discussionmentioning

confidence: 99%

“…However, the causal linkage between CHD and depression is still incompletely understood [5]. CHD accompanied by depression may be caused by multiple factors, including physiological and psychosocial factors, such as inflammation, endothelial dysfunction, hypothalamic–pituitary–adrenal axis hyperactivity, various behavioral factors, gut microbiome, and endocrine signaling [5, 6].…”

Section: Introductionmentioning

confidence: 99%

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Prevalence and predisposing factors of depressive symptoms in patients with stable coronary artery disease: a cross-sectional single-center study

Zhu

Chen

et al. 2019

Aging

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The incidence of depressive symptoms in patients with stable coronary artery disease (SCAD) has significantly increased. However, its pathogenesis and treatment mechanisms are still incompletely understood. In this study, 144 patients with SCAD were recruited. Depressive symptoms of patients with SCAD were evaluated using Zung Self-Rating Depression Scale during hospitalization, and the patients were categorized into two subgroups: the non-depressive and depressive groups (further divided into mild and moderate/severe depressive groups). The rate of moderate/severe depressive symptoms in patients with SCAD was 18.8%. The mean age of patients in the depressive and mild depressive groups was older than that of those in the non-depressive group, and patients in the moderate/severe depressive group had higher high-density lipoprotein (HDL) and lower creatinine (Cr) levels. Binary logistic regression analysis showed that lower low-density lipoprotein (LDL) levels were significantly associated with increased risks of mild depressive symptoms, whereas higher HDL and lower Cr levels were significantly associated with moderate/severe depressive symptoms, suggesting that patients with SCAD were prone to experience depressive symptoms, especially in the elderly. Abnormality in LDL, HDL, and Cr levels might contribute to the depressive symptoms.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Prevalence and predisposing factors of depressive symptoms in patients with stable coronary artery disease: a cross-sectional single-center study

Zhu

Chen

et al. 2019

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“…A medicina tradicional chinesa trata coração e mente como uma unidade funcional, nesse contexto, quando há um processo que provoca a disfunção de uma das partes dessa unidade funcional, cessase a harmonia entre ambos, por isso, dentro de um ponto de vista mais científico, pode-se dizer que as doenças arteriais coronarianas possuem a capacidade de desencadear transtornos mentais como, por exemplo, a depressão e, em contrapartida, a ocorrência desse transtorno pode predispor a disfunções cardiovasculares (WU et al, 2019).…”

Section: Introductionunclassified

“…Diante desse contexto supracitado, é relevante abordar ainda que a depressão é caracterizada clinicamente pela aparição do humor depressivo, fadiga persistente e redução da vontade de realização de atividades diárias (WU et al, 2019).…”

Section: Introductionunclassified

Implicações Na Saúde Mental De Idosos Diante Do Contexto Pandêmico Da Covid-19

Alves¹,

Ribeiro²,

Santos³

et al. 2021

Tópicos Em Ciências Da Saúde

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Resumo: Nos últimos anos, devido ao aumento da interação entre o homem e o animal, observa-se que esta relação provoca reações positivas, tanto físicas quanto psicológicas nos humanos, além de promover avanços na socialização. Desse modo, com o interesse em estudar o seu potencial terapêutico, a Zooterapia começou a ganhar força nas últimas décadas, sendo conhecida como Terapia Assistida por Animais (TAA). Em suma, tendo em vista a importância da Zooterapia, objetiva-se nesse artigo descrever e caracterizar por meio de revisões bibliográficas, a importância da Terapia Assistida por Animais no tratamento de doenças psicológicas, o benefício da relação do homem com o cão, multiprofissionais na TAA, bem como os exames clínicos necessários em zooterapeutas para garantir a segurança dos pacientes assistidos. Os animais de estimação são vistos como membros ativos no processo terapêutico, uma vez que a TAA proporciona uma melhora psicológica, social e cognitiva do paciente, além de promover o bem-estar por meio de atividades multiprofissionais.

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“…Psychological stress affects the neuroendocrine system and immune system, which in turn acts on the nervous system, causing anxiety and depression-like behaviors [ 3 ]. Psychological intervention has become the focus in the prevention of emotional disorders in heart disease patients [ 4 ]. Aerobic exercise can reduce the risk of adverse cardiovascular events in CHD patients and reduce the severity of anxiety and depression [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

Five‐Animal Frolics Exercise Improves Anxiety and Depression Outcomes in Patients with Coronary Heart Disease: A Single‐Blind Randomized Controlled Trial

Jiang

Chi

Wang

et al. 2020

Evidence-Based Complementary and Alternative Medicine

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Introduction. The patients with coronary heart disease (CHD) always have emotional implications. As the branch of traditional Chinese medicine, Five-Animal Frolics Exercise (FAE) is a popular mind-body exercise in China and shown to improve emotional wellbeing. Aim. We aimed to explore the effects of FAE on the emotional disorders of CHD patients. Methods. CHD patients were assigned into an experiment group (EG, FAE) and a control group (CG, routine nursing care). We measured serum levels of miR-124 and miR-135 and scores of the Hamilton Depression/Anxiety scale (HAMD/HAMA), Self-Rating Anxiety Scale (SAS), the Self-Rating Depression Scale (SDS), Short Form 36 Health Survey Questionnaire (SF-36), and Pittsburgh Sleep Quality Index (PSQI). Results. After a 3-month FAE intervention, serum levels of miR-124 and miR-135 and the scores of HAMD/HAMA, SAS, SDS, and PSQI in the EG group were lower than those in the CG group, while SF-36 scores in the EG group were higher than those in the CG group (p<0.05). Serum levels of miR-124 and miR-135 had a strong relationship with SAS and SDS scores (p<0.05). Discussion/Implications for Practice. The study suggests that FAE intervention controls anxiety and depression outcomes and improves life quality in CHD patients by affecting serum levels of miR-124 and miR-135.

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New Insights Into the Comorbidity of Coronary Heart Disease and Depression

Cited by 47 publications

References 159 publications

Prevalence and predisposing factors of depressive symptoms in patients with stable coronary artery disease: a cross-sectional single-center study

Prevalence and predisposing factors of depressive symptoms in patients with stable coronary artery disease: a cross-sectional single-center study

Implicações Na Saúde Mental De Idosos Diante Do Contexto Pandêmico Da Covid-19

Five‐Animal Frolics Exercise Improves Anxiety and Depression Outcomes in Patients with Coronary Heart Disease: A Single‐Blind Randomized Controlled Trial

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