New Insights into the Gametogenesis of Biomphalaria glabrata (Mollusca, Gastropoda, Pulmonata): Implications for Histopathological Assessment

Rodrigues, Cândido Carvalho; Caixeta, Maxwell Batista; Rocha, Thiago Lopes

doi:10.1590/1678-4324-2021200574

Cited by 3 publications

(2 citation statements)

References 49 publications

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“…The histological structures of the hermaphrodite gland of untreated T. pisana snails reported in this study showed different stages of spermatogenesis and oogenesis in addition to highlighting the follicular and germinal layers with their cells. Similar structures were illustrated by Morad (2021) for hermaphrodite gland of Eobania vermiculata snails and Rodrigues et al. (2021) for that of Biomophalaria alexandrina .…”

Section: Discussionsupporting

confidence: 68%

Effect of Eucalyptus globulus oil and Ricinus communis methanolic extract as potential natural molluscicides on the reproductive biology and some antioxidant enzymes of the land snail, Theba pisana

Desouky¹,

El-Atti²,

Elsheakh³

et al. 2022

Heliyon

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Section: Discussionsupporting

confidence: 68%

Effect of Eucalyptus globulus oil and Ricinus communis methanolic extract as potential natural molluscicides on the reproductive biology and some antioxidant enzymes of the land snail, Theba pisana

Desouky¹,

El-Atti²,

Elsheakh³

et al. 2022

Heliyon

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“…6 , Table S16 ). In the developing ovotestis of juvenile snails, a strong early expression of genes involved in spermatogenesis might be expected because B. glabrata is a functionally protandrous species [ 61 ], and the number of cells involved in spermatogenesis is much greater than in oogenesis [ 62 ], so would be easier to detect.…”

Section: Resultsmentioning

confidence: 99%

Different metazoan parasites, different transcriptomic responses, with new insights on parasitic castration by digenetic trematodes in the schistosome vector snail Biomphalaria glabrata

Lu,

Bu,

Laidemitt

et al. 2024

BMC Genomics

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Background Gastropods of the genus Biomphalaria (Family Planorbidae) are exploited as vectors by Schistosoma mansoni, the most common causative agent of human intestinal schistosomiasis. Using improved genomic resources, overviews of how Biomphalaria responds to S. mansoni and other metazoan parasites can provide unique insights into the reproductive, immune, and other systems of invertebrate hosts, and their responses to parasite challenges. Results Using Illumina-based RNA-Seq, we compared the responses of iM line B. glabrata at 2, 8, and 40 days post-infection (dpi) to single infections with S. mansoni, Echinostoma paraensei (both digenetic trematodes) or Daubaylia potomaca (a nematode parasite of planorbid snails). Responses were compared to unexposed time-matched control snails. We observed: (1) each parasite provoked a distinctive response with a predominance of down-regulated snail genes at all time points following exposure to either trematode, and of up-regulated genes at 8 and especially 40dpi following nematode exposure; (2) At 2 and 8dpi with either trematode, several snail genes associated with gametogenesis (particularly spermatogenesis) were down-regulated. Regarding the phenomenon of trematode-mediated parasitic castration in molluscs, we define for the first time a complement of host genes that are targeted, as early as 2dpi when trematode larvae are still small; (3) Differential gene expression of snails with trematode infection at 40dpi, when snails were shedding cercariae, was unexpectedly modest and revealed down-regulation of genes involved in the production of egg mass proteins and peptide processing; and (4) surprisingly, D. potomaca provoked up-regulation at 40dpi of many of the reproduction-related snail genes noted to be down-regulated at 2 and 8dpi following trematode infection. Happening at a time when B. glabrata began to succumb to D. potomaca, we hypothesize this response represents an unexpected form of fecundity compensation. We also document expression patterns for other Biomphalaria gene families, including fibrinogen domain-containing proteins (FReDs), C-type lectins, G-protein coupled receptors, biomphalysins, and protease and protease inhibitors. Conclusions Our study is relevant in identifying several genes involved in reproduction that are targeted by parasites in the vector snail B. glabrata and that might be amenable to manipulation to minimize their ability to serve as vectors of schistosomes.

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Phthalate exposure influences mating behavior and sperm morphology in an aquatic ecotoxicology model system

Guevara,

Patel,

et al. 2024

Preprint

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Phthalates are a group of chemicals used to make plastics more durable, found in applications from cosmetics, lubricating oils, and flooring to soap, shampoo, and hairspray (CDC, 2021). Phthalates are also now known to be endocrine disruptors with connections to adverse reproductive outcomes in animals, including humans. Here, we evaluate the potential effects of a widely used phthalate ester, dimethyl phthalate (DMP), on male reproduction in a freshwater snail. DMP is found in industrial applications like solid rocket propellant as well as consumer products such as insect repellents and plastics. While there is some evidence that DMP negatively affects reproduction, especially in females, we still know very little about potential DMP effects on males. We addressed this important knowledge gap by testing the effects of DMP onPotamopyrgus antipodarum, a prosobranch snail native to New Zealand. These snails are very sensitive to water conditions and environmental chemicals, including endocrine-disrupting compounds, and are thus rising in prominence as water-quality sentinels and ecotoxicology models. We exposed experimental groups of maleP. antipodarumto one of three different concentrations of DMP and characterized mating behavior and sperm morphology as a function of DMP exposure. As DMP exposure levels increased, we found that mating frequency decreased and that sperm morphology was increasingly altered relative to control males. Altogether, study outcomes suggest DMP exposure in male animals could have negative effects on reproduction, with particular relevance in aquatic and marine environments that are especially likely to harbor leached endocrine-disrupting chemicals.

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New Insights into the Gametogenesis of Biomphalaria glabrata (Mollusca, Gastropoda, Pulmonata): Implications for Histopathological Assessment

Cited by 3 publications

References 49 publications

Effect of Eucalyptus globulus oil and Ricinus communis methanolic extract as potential natural molluscicides on the reproductive biology and some antioxidant enzymes of the land snail, Theba pisana

Effect of Eucalyptus globulus oil and Ricinus communis methanolic extract as potential natural molluscicides on the reproductive biology and some antioxidant enzymes of the land snail, Theba pisana

Different metazoan parasites, different transcriptomic responses, with new insights on parasitic castration by digenetic trematodes in the schistosome vector snail Biomphalaria glabrata

Phthalate exposure influences mating behavior and sperm morphology in an aquatic ecotoxicology model system

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