New Inventions Anæsthetic Methods in Infants

Dinsdale, Tom

doi:10.1111/j.1365-2044.1954.tb01564.x

Cited by 5 publications

(2 citation statements)

References 1 publication

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“…These findings suggested that the full value of the clinical use of d-tubocurarine remained to be studied. Antidepolarizing relaxants had been used successfully by a number of anaesthetists in the newborn (Auld, 1952;Fairlie, 1954;Dinsdale, 1954;Payne, 1955). Recently in an unselected series of 215 neonates only two instances of immediate postoperative difficulties were observed following the use of d-tubocurarine (Bush and Stead, 1962).…”

Section: The Neonatementioning

confidence: 99%

The Use of Muscle Relaxants in Infants and Children

Bush

1963

British Journal of Anaesthesia

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The belief that the use of muscle relaxants in infants and children is both unnecessary and dangerous has not been substantiated by subsequent clinical experience. The important advances that have been made recently in paediatric anaesthesia are due largely to the introduction of muscle relaxants, which have reduced the need for toxic agents to a minimum and have emphasized the importance of control of pulmonary ventilation. Furthermore, muscle relaxants now play an important role in the management of a wide variety of medical and surgical conditions.

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Section: The Neonatementioning

confidence: 99%

The Use of Muscle Relaxants in Infants and Children

Bush

1963

British Journal of Anaesthesia

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“…(2.2 mg/kg) body weight during surgical repair of oesophageal atresia. Dinsdale (1954) briefly mentioned that he used d-tubocurarine, usually in a dose of 1 mg, for neonatal operations. In the anaesthetic management of the repair of oesophageal atresia Payne (1955) used d-tubocurarine in a dose of 0.2 mg/lb.…”

mentioning

confidence: 99%

The Use of D-Tubocurarine in Neonatal Anaesthesia

Bush

Stead

1962

British Journal of Anaesthesia

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d-Tubocurarine was used in an unselected series of 215 neonates undergoing surgery with only two cases of immediate postoperative respiratory difficulty. The neonate is more sensitive to d-tubocurarine than the adult but this sensitivity decreases during the neonatal period and may be partially explained by changes at the motor end plate and by a diminution in extracellular volume. Overdosage, potentiation by ether and antibiotics, hypothermia and failure to use anticholinesterase drugs are potent causes of immediate postoperative respiratory difficulties, which have been wrongly attributed to d-tubocurarine.

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Current pediatric references

Schwartz

1954

The Journal of Pediatrics

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New Inventions Anæsthetic Methods in Infants

Cited by 5 publications

References 1 publication

The Use of Muscle Relaxants in Infants and Children

The Use of Muscle Relaxants in Infants and Children

The Use of D-Tubocurarine in Neonatal Anaesthesia

Current pediatric references

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