New lignans from Syringa reticulata var. mandshurica

Phytochemical and pharmacological progress on the genus Syringa

“…mandshurica [32] 58 Mandshuricol Bleaves S. reticulata var. mandshurica [32] 59 (+)-Lariciresinolseeds crust S. oblata [25] 60 (+)-Lariciresinol 4- O - β -D-glucopyranosidebarks S. vulgaris [29] 61 Balanophoninroots and stems S. pinnatifolia var. alashanensis [30] 62 (+)-Lariciresinol 4′- O - β -D-glucopyran -osyl-(1→3)- β -D-glucopyranosideleaves S. reticulata [19] 63 Syripinnalignin Aroots and stems S. pinnatifolia var.…”

“…alashanensis [30,31], and S. reticulata var. mandshurica [32]. Syringa species have 34 lignans and their glycosides ( 47 – 80 ), including monoepoxylignans ( 47 – 60 , 62 ) and their dimers ( 63 and 64 ), neolignans ( 61 , 73 – 74 ), cyclolignans ( 65 and 66 ), simple lignans ( 67 – 72 ), and bisepoxylignans ( 75 – 80 ).…”

“…Lignans also exhibit many bioactivities. For example, compound 50 has anti-oxidant activity [10]; compounds 57 and 58 have antifungal activities [32]; and compound 75 has significant cytotoxic, antihypertensive, anti-inflammatory, and anti-oxidant activities [5]. …”

Secoiridoid Glucosides from the Twigs of <i>Syringa oblata</i> var. <i>dilatata</i> and Their Neuroprotective and Cytotoxic Activities

“…[6][7][8][9] Previous phytochemical investigations regarding this genus have reported the isolation of secoiridoid glucosides, lignans, and phenolic compounds with anti-radical scavenging and cytotoxic activity. 10) However, only a few phytochemical studies on S. oblata var.…”

“…dilatata. The column chromatographic purification of the EtOAc-soluble fraction led to the isolation of two new secoiridoid glucosides, dilatioside A-B (1-2), along with thirteen known ones (3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15). The chemical structures of the isolated compounds were determined by their NMR spectroscopic data, MS, and methanolysis.…”