New members to Arctic-like lineage of canine distemper virus from Turkey

Pathological and Molecular Investigation of Canine Distemper Virus: Phylogenetic analysis of co-circulating genetic lineages based on H and F genes

“…The detected eld CD viruses were found to be among the European strains (Ozkul et al 2004;Oğuzoğlu et al 2018;Yılmaz et al 2021). Sequences obtained in the phylogenetic analysis generated with the H gene sequence, were observed to be localized to a branch close to the Italian ancestry, including wild CDV strains under the Arctic CDV lineage (Koç et al 2021). As a result of the studies, the presence of European and Arctic strains in Turkey has been determined separately until now.…”

Persistent and Severe Viral Replication in PBMCs with Moderate Immunosuppression Served an Alternative Novel Pathogenic Mechanism for Canine Morbillivirus

“…Phylogenetic analysis revealed that the epidemic CDV isolates clustered to geographically distributed lineages other than the vaccine lineage of America-1 or America-2, which raised the question as to protection efficiency of vaccine strains ( 11 ). The high diversity of H protein conferred important roles in site mutations and antigenic drifts ( 30 ). The amino acid sequence alignment results based on the H protein of wtHBF-1 and the Onderstepoort strain demonstrated that 57 residues were different (data not shown).…”

Pathological and molecular investigation of canine distemper virus: Phylogenetic analysis of co-circulating genetic lineages in Türkiye

“…At that time, the viruses belonging to this lineage have been found to be responsible for the deaths of seals in northwestern Europe and Siberia (Likhoshway et al, 1989;Visser et al, 1990). Since then, the occurrence of Arctic lineage strains has been reported from various parts of the world (America, China, Iran), as well as from European countries including Hungary, Italy and Türkiye (Demeter et al, 2007;Namroodi et al, 2015;Nguyen et al, 2017;Mira et al, 2018;Koç et al, 2021). Studies have also shown that both European and Arctic strains co-circulate in many countries including Hungary and Italy (Demeter et al, 2007;Ricci et al, 2021).…”

“…The first detected field CDVs have been found to belong to the European strains (Ozkul et al, 2004;O guzo glu et al, 2018;Yılmaz et al, 2022). In phylogenetic analysis, based on the H gene sequences, the Turkish sequences have appeared in a branch close to the Italian lineage, including wild CDV strains under the Arctic CDV lineage (Koç et al, 2021). The presence of European and Arctic strains in Türkiye has been detected separately.…”