New Metal Complexes with AZO ligand; Synthesis, Spectral Characterisation and Biological Evaluation

Abstract

The new Azo ligand and its metal complexes have been prepared and characterized The reaction of 4-nitroaniline and 2-hydroxy-1-naphthaldehyde in a 1:1 mole ratio resulted in the synthesis of ((E)-2-hydroxy-3-((4-nitrophenyl) diazenyl)-1-naphthaldehyde) (HL). The separation of monomeric complexes was accomplished by reacting ((E)-2-hydroxy-3-((4-nitrophenyl)diazenyl)-1-naphthaldehyde) (HL) with Cr, Mn II, Co II, Ni II, and Cu II metal ions in a mole ratio of 2:1 (L: M). Elemental microanalysis, magnetic susceptibility, conductance, FT-IR, electronic spectra, and 1HNMR, 13C-NMR, and mass spectra were among the analytical and spectroscopic techniques used to describe the products. Based on the data collected during the characterization process, six coordinates were determined. The ligand and its complexes were tested against certain bacteria and fungi. The findings acquired suggested that the metal complexes are more active against a variety of organisms have been studied as compared to the free ligand. Keywords: ((E)-2-hydroxy-3-((4-nitrophenyl) diazenyl)-1-naphthaldehyde); Azo ligand; Candida and Rhizopus porium; 2-hydroxy-1-naphthaldehyde; Metal Complexes.

New Metal Complexes Derived from Azo Linked Schiff-Base ligand: Synthesis, Spectral Investigation and Biological Evaluation

“…The ability of Schiff bases to interact and form stable complexes with a wide range of metal ions makes them a crucial ligand in coordination chemistry [6,7]. Furthermore, the applications of Schiff bases are diverse and include their role in fields such as inorganic and analytical chemistry [8,9], as well as medicinal and pharmacological areas [10] and biological [11] Schiff bases with azo moieties have a wide range of applications beyond their use in biological systems.…”

Synthesis, Structural Characterisation and Biological Activity; New Metal Complexes Derived from Semicarbazone Ligand

“…For example, the fact that transition metal complexes of Schiff base ligands with "O" and "N" donor atoms have antibacterial, antifungal, and anti-inflammatory characteristics makes them particularly significant 4 , an anticonvulsant 5,6 , an analgesic 7 , an anthelmintic 8 , an antitubercular 9 , and an antioxidant 10 . Not very long ago, we attended the installation of the base Schiff and its complexes [11][12][13] . The ligand was synthesized from the reaction of the Mannich precursor ((((4) (tributyl)-2-(((S))-(phenylamino)(p-tolyl)methyl) cyclohexane-1-one)) with Semicarbazone, then the prepared compounds were tested, because of its effectiveness against bacteria and fungal organisms.…”