2021
DOI: 10.51316/jst.148.etsd.2021.31.1.8
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New Method of 2-Arylbenzoxazole Synthesis from 2-Aminophenol Derivatives and Benzaldehyde Using Sulfur as an Oxidant 

Abstract: In previous studies, the synthesis of 2-arylbenzoxazole derivatives required strongly acidic conditions, prolonged heating at high temperatures and significant amounts of expensive/toxic transition metal catalysts. A major drawback of using oxygen as an oxidant is the risk of explosion of flammable organic substrates. Moreover, due to its gaseous state, exact stoichiometric control of oxygen amounts used in the reaction is not readily possible. Therefore, new methods of mellow conditions with eco-friendly agen… Show more

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