2016
DOI: 10.5897/sre2015.6378
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New methodology for microarray spot segmentation and gene expression analysis

Abstract: DNA microarray analysis is the main core in genome mapping. Each microarray image contains millions of information about genes. Microarray analysis is considered one of the most recent and important technologies in exploring the genome. One of the key steps in microarray analysis is to extract gene information from the gene spots, these information represent gene expression levels in the microarray. This paper proposes a new methodology to improve microarray spot analysis based on spot extracted segments. It c… Show more

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Cited by 2 publications
(1 citation statement)
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“…Also for this kind of problems, Information Theory provides quantization strategies, but at the cost of much greater estimation complexity [15]. In genomic and proteomic analyses, the adaptive thresholding is exploited for the study of differential microarray spot intensities [16,17]. The objects analysed in the images can be static or in motion, multiple or single.…”
Section: Introductionmentioning
confidence: 99%
“…Also for this kind of problems, Information Theory provides quantization strategies, but at the cost of much greater estimation complexity [15]. In genomic and proteomic analyses, the adaptive thresholding is exploited for the study of differential microarray spot intensities [16,17]. The objects analysed in the images can be static or in motion, multiple or single.…”
Section: Introductionmentioning
confidence: 99%