New norditerpenoids from Cespitularia hypotentaculata

Shen, Ya‐Ching; Lin, Jann-Fang; Wu, Ying-Ru; Chang, Jiun-Yang; Duh, Chang‐Yih; Lo, Kuang Liang

doi:10.1016/j.tetlet.2006.06.178

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Cited by 27 publications

(18 citation statements)

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“…On the basis of the above data, the remaining two degrees of unsaturation suggested that compound 1 contains a bicyclic norverticillane ring similar to that previously reported for cespitularin M [10]. The b-configuration of the OH group at C(6) was confirmed by comparison of the previously reported norditerpenoid cespihypotin A [8]. We assume that 1 has the same absolute configuration at C(1) as other naturally occurring cespitularines and taxoids [15].…”

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confidence: 85%

ChemInform Abstract: Verticillane and Norverticillane Diterpenoids from the Formosan Soft Coral Cespitularia hypotentaculata.

2010

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confidence: 85%

ChemInform Abstract: Verticillane and Norverticillane Diterpenoids from the Formosan Soft Coral Cespitularia hypotentaculata.

2010

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“…Marine soft corals are an excellent source of secondary metabolites with novel structures and interesting biological functions [1,2,3,4,5]. Members of the genus Cespitularia , along with morphologically similar Xenia species, inhabit the coral reefs along the coasts of Taiwan.…”

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confidence: 99%

Cespitulones A and B, Cytotoxic Diterpenoids of a New Structure Class from the Soft Coral Cespitularia taeniata

et al. 2014

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Two novel diterpenoids, cespitulones A (1) and B (2), were isolated from extracts of the soft coral Cespitularia taeniata. Both compounds possess an unprecedented bicyclo [10.3.1] ring system with C-C bond connections between C-10 and C-20, and between C-20 and C-11. Their structures were elucidated on the basis of extensive spectroscopic analyses. Compound 1 exhibited significant cytotoxicity against human medulloblastoma and colon adenocarcinoma cancer cells.

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“…HR-ESI-MS, 13 C-NMR, and DEPT spectra established its molecular formula as C 19 H 28 O 3 , indicating six degrees of unsaturation. -Compound 1 was isolated as a colorless amorphous solid.…”

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confidence: 99%