Background: The participation of mental health professionals in multidisciplinary care teams for heart transplantation has become an international standard practice. The contribution of these professionals in this setting, which involves assessment and interventions, has not been the subject of systematic study. Methods: This paper explores how psychotherapists contribute to multidisciplinary decision making and care in transplant teams before, during, and after transplantation. To illustrate, it uses the case of a 19-year-old woman with anorexia nervosa who underwent heart transplant at a large transplantation center in Germany. She received psychotherapeutic interventions intended to lower the risk of non-adherence. Results: This first reported case of heart transplant in a patient with a previous diagnosis of anorexia nervosa also documents psychotherapeutic interventions that were favorable for sustainable weight-gain and how the multidisciplinary environment enabled their development and implementation. We provide details on the contribution of the psychologist in the case, including hypnotherapy interventions and adjustments in routine nursing practices. Conclusions: This paper shows how mental health professionals working in multidisciplinary teams improve patient outcomes in organ transplantation. In order to collect and systematize clinical knowledge of psychotherapeutic interventions for transplant candidates with mental health issues, additional studies with multiple centers, multiple cases, and a range of mental health disorders are needed.