New Onset Granulomatosis with Polyangiitis Associated with COVID-19

Bressler, Moshe Y.; Pathak, Naeha; Cervellione, Kelly; Bagheri, Farshad; Epstein, Edward; Mir, Adnan; Tamez, Rebecca

doi:10.1155/2021/8877292

Cited by 16 publications

(17 citation statements)

References 12 publications

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“…We excluded 24 patients: 10 did not have objective evidence of vasculitis, 7 did not fulfill established criteria, 3 where SARS-CoV-2 was the direct causative agent, 2 with insufficient information, 1 with no proven COVID-19 and 1 duplicated case. Forty-six cases from 43 articles fulfilled criteria and/or nomenclature for immune-mediated vasculitides and were included [ 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 ] ( Supplementary file ).…”

Section: Resultsmentioning

confidence: 99%

New Onset of Autoimmune Diseases Following COVID-19 Diagnosis

Gracia‐Ramos

Martín‐Nares

Hernández-Molina

2021

Cells

203

158

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There is growing evidence that coronavirus disease 2019 (COVID-19) can lead to a dysregulation of the immune system with the development of autoimmune phenomena. The consequence of this immune dysregulation ranges from the production of autoantibodies to the onset of rheumatic autoimmune disease. In this context, we conducted a systematic review to analyze the current data regarding the new-onset systemic and rheumatic autoimmune diseases in COVID-19 patients. A literature search in PubMed and Scopus databases from December 2019 to September 2021 identified 99 patients that fulfilled the specific diagnostic/classification criteria and/or nomenclature for each rheumatic autoimmune disease. The main diseases reported were vasculitis and arthritis. Idiopathic inflammatory myopathies, systemic lupus erythematosus, and sarcoidosis were also reported in a limited number of patients, as well as isolated cases of systemic sclerosis and adult-onset Still’s disease. These findings highlight the potential spectrum of systemic and rheumatic autoimmune diseases that could be precipitated by SARS-CoV-2 infection. Complementary studies are needed to discern the link between the SARS-CoV-2 and new onset-rheumatic diseases so that this knowledge can be used in early diagnosis and the most suitable management.

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Section: Resultsmentioning

confidence: 99%

New Onset of Autoimmune Diseases Following COVID-19 Diagnosis

Gracia‐Ramos

Martín‐Nares

Hernández-Molina

2021

Cells

203

158

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“…A further case report of c-ANCA positive crescentic GN with alveolar haemorrhage is also reported [ 121 ]. Bressler et al report a 46 year old man who developed renal involvement as part of AAV concomitant with COVID-19 and was treated with corticosteroids and Rituximab [ 122 ]. Weston et al report a 12 year old girl with likely previous asymptomatic infection with SARS-CoV-2 who developed biopsy proven vasculitis associated with myeloperoxidase antibodies and needing aggressive management through corticosteroids, Rituximab and Cyclophosphamide [ 123 ].…”

Section: Resultsmentioning

confidence: 99%

Rheumatological complications of Covid 19

Zacharias

Dubey

Koduri

et al. 2021

Autoimmunity Reviews

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Introduction COVID-19 has caused unprecedented hardships in the 21st century with more than 150 million infections. Various immunological phenomena have been described during the course of the infection, and this infection has also triggered autoimmunity. Rheumatological illnesses have been described following resolution of the acute infection; hence we sought to conduct a review of the rheumatological complications of COVID-19. Methods We conducted a literature search for articles relating to sequelae of COVID-19 from Jan 2020 to 30th April 2021. Results We found a number of reports of inflammatory arthritis after SARS-CoV-2 infection. SLE and renal disease have been described, and vasculitis also appears to be a common complication. Rhabdomyolysis and myositis has also been reported in a number of patients. We also found some evidence of large vessel vasculitis in ‘long COVID’ patients. Conclusions This review highlights a number of important complications such as inflammatory arthritis, lupus-like disease, myostis and vasculitis following SARS-CoV-2 infection.

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“… 10 , 11 , 12 Presentation may be extremely variable and, in cases of lung involvement, the differential diagnosis between idiopathic vasculitis and COVID‐19 may be challenging. 8 , 9 On the other hand, there have not yet been any reports of cases of patients whose rheumatic condition has worsened or even relapsed after vaccination against COVID‐19.…”

Section: Discussionmentioning

confidence: 99%

“…5 It is therefore not surprising that SARS-CoV-2 may trigger the development and/or relapse of certain autoimmune disorders, including vasculitis. To the best of our knowledge, few papers have reported cases of COVID-induced vasculitis in adulthood: these have usually concerned IgA-related, 6,7 antineutrophil cytoplasmic antibodies (ANCA)-associated, 8,9 or large-vessel forms. [10][11][12] Presentation may be extremely variable and, in cases of lung involvement, the differential diagnosis between idiopathic vasculitis and COVID-19 may be challenging.…”

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confidence: 99%