New-onset insomnia among cancer patients undergoing chemotherapy: prevalence, risk factors, and its correlation with other symptoms

Hoang, Huong; Molassiotis, Alex; Chan, Choi Wan; Nguyen, Thi Hương; Nguyen, Van Liep

doi:10.1007/s11325-019-01839-x

Cited by 38 publications

(50 citation statements)

References 53 publications

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“…The sleep quality of insomnia patients after gastric cancer surgery was positively correlated with fatigue and depression (Pearson = 0.428 and 0.261, P = 0.000 and 0.005), but not correlated with anxiety (P = 0.527). Hoang HTX et al also found that the incidence and severity of insomnia in cancer patients had nothing to do with the characteristics of the participants, cancer information, or treatment factors, but were related to the emotional score of the participants [6]. The results of a systematic review also pointed out that patients with insomnia and mood have a two-way effect [49].…”

Section: Discussionmentioning

confidence: 99%

“…As a result, the patient loses confidence in the treatment effect, and insomnia also occurs or worsens [45,46]. The result of a cross-sectional study looking at new-onset insomnia in cancer patients during chemotherapy showed that 42.8% of the 213 patients surveyed reported insomnia, and 31.9% of them reported severe insomnia [6]. In addition, the cerebral toxicity caused by the use of chemotherapeutic drugs contributes to the progression of brain inflammation by affecting the production and distribution of pro-inflammatory cytokines [47].…”

Section: Discussionmentioning

confidence: 99%

“…Improving the quality of life of cancer patients has gradually become the focus of attention and urgent problems to be solved for patients, families, society, and clinicians. Symptom management of tumor patients has gradually become a hot spot for medical personnel and scientific researchers [6,7].…”

Section: Introductionmentioning

confidence: 99%

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The characteristics and related factors of insomnia among postoperative patients with gastric cancer: a cross-sectional survey

Zhu

et al. 2021

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Purpose This study aims to explore the characteristics and related factors of insomnia of patients after operation for gastric cancer. Methods A cross-sectional survey was carried out and finally 115 patients with insomnia after operation for gastric cancer were included. The general information, gastric cancer-related information, sleep quality, and other symptoms were investigated. Results ① The Pittsburgh sleep quality index score of most insomnia patients after gastric cancer surgery was 11-15 points, and the sleep quality rating was “poor”. ② The sleep quality of patients with insomnia after surgery for gastric cancer is related to the number of chemotherapy cycles, fatigue, and depression. ③ The probability of reduced sleep quality with the number of chemotherapy cycles >6 is 3.640 times that of ≤6. The probability of reduced sleep quality during moderate to severe fatigue was 4.390 times that of patients with no or mild fatigue. Conclusion Attention to related factors may be associated with improvement of sleep quality in patients with gastric cancer after surgery.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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The characteristics and related factors of insomnia among postoperative patients with gastric cancer: a cross-sectional survey

Zhu

et al. 2021

Support Care Cancer

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“…Hoang HTX et al also found that the incidence and severity of insomnia in cancer patients had nothing to do with the characteristics of the participants, cancer information or treatment factors, but were related to the emotional score of the participants. [6] The results of a systematic review also pointed out that patients with insomnia and mood have a two-way effect. [30] The hypothalamus, hippocampus and other brain tissues regulate emotion and sleep at the same time by secreting neuropeptides and neurotransmitters, so that the two are connected.…”

Section: Discussionmentioning

confidence: 99%

“…Symptom management of tumor patients has gradually become a hot spot for medical personnel and scienti c researchers. [6,7] The incidence of insomnia in patients with malignant tumors is 52.6%-67.4%, which is twice that of the general population. [8,9] However, if effective intervention is not given, chronic insomnia often develops.…”

Section: Introductionmentioning

confidence: 99%

The Characteristics, Related Factors and Risk Factors of Insomnia among Postoperative Patients with Gastric Cancer: A Cross-sectional Survey

Zhu

et al. 2021

Preprint

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Purpose This study aims to explore the characteristics, related factors and risk factors of insomnia of patients after operation for gastric cancer. Methods A cross-sectional survey was carried out and finally 115 patients with insomnia after operation for gastric cancer were included. The general information, gastric cancer related information, sleep quality and other symptoms were investigated. Results ①The Pittsburgh sleep quality index score of most insomnia patients after gastric cancer surgery was 11–15 points, the sleep quality rating was “Poor”. ②The sleep quality of patients with insomnia after surgery for gastric cancer is related to the number of chemotherapy cycles, fatigue and depression. ③The risk of reduced sleep quality with the number of chemotherapy cycles > 6 is 3.640 times that of ≤ 6. The risk of reduced sleep quality during moderate to severe fatigue was 4.390 times that of patients with no or mild fatigue. Conclusion Attention to related factors and risk factors may be associated with improvement of sleep quality in patients with gastric cancer after surgery.

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Mediating effects of rumination on insomnia in cancer survivors: Influences of cancer‐related fatigue, fear of recurrence, and psychological distress

Amani,

Mazaheri,

Malekzadeh Moghani

et al. 2024

Cancer Medicine

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BackgroundWhile advancements in cancer treatments have improved survival rates, they also lead to adverse effects such as insomnia, which significantly impacts survivors' sleep quality.ObjectiveThis study explores the influence of cancer‐related fatigue (CRF), Fear of Cancer Recurrence (FCR), and psychological distress, with rumination serving as a mediating factor, on the insomnia experienced by cancer survivors.MethodsThe study involved 220 cancer survivors attending Shohada‐e‐Tajrish Hospital's oncology center in Tehran, Iran. Participants were selected through convenience sampling and completed several questionnaires: the Insomnia Severity Index, Fear of Cancer Recurrence Inventory, Cancer Fatigue Scale, Kessler Psychological Distress Scale, and Rumination Response Scale.ResultsThe results showed that the tested model had a good fit, and the correlation matrix demonstrated significant positive correlations between CRF (0.46), FCR (0.15), psychological distress (0.55), and rumination (0.42) with insomnia in cancer survivors (p < 0.05). Notably, CRF (B = 0.356, p < 0.001) and psychological distress (B = 0.339, p < 0.001) affect insomnia both directly and indirectly through mediation by rumination, while the impact of FCR on insomnia was indirectly significant (B = 0.73, p < 0.05).ConclusionThe findings suggest that interventions focused on managing rumination could be potential targets to alleviate insomnia and improve the sleep quality of cancer survivors.

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New-onset insomnia among cancer patients undergoing chemotherapy: prevalence, risk factors, and its correlation with other symptoms

Cited by 38 publications

References 53 publications

The characteristics and related factors of insomnia among postoperative patients with gastric cancer: a cross-sectional survey

The characteristics and related factors of insomnia among postoperative patients with gastric cancer: a cross-sectional survey

The Characteristics, Related Factors and Risk Factors of Insomnia among Postoperative Patients with Gastric Cancer: A Cross-sectional Survey

Mediating effects of rumination on insomnia in cancer survivors: Influences of cancer‐related fatigue, fear of recurrence, and psychological distress

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