Energy services are especially expensive on remote islands due to longer and more unstable fuel supply chains. In this paper, different renewable energy systems utilizing locally available biomass and solar energy are proposed as alternatives for a hotel resort on Neil Island, India. Based on local demand data, commercial information, and scientific literature, four cases are modelled with the simulation software HOMER and their economic, energetic, as well as ecological (3E) performances are compared. The robustness of each case configuration is tested with a sensitivity analysis. The results show that a biomass-based, solar-assisted combined cooling, heating, and power (CCHP) system offers an economic saving potential of more than 500,000 USD over twenty years and could decrease CO2 emissions by 365 t per year. When not applying CCHP measures, system performance is significantly worsened. A solar and battery-assisted diesel generator system shows similar economic outcomes as the CCHP system but worse ecological performance. Implementing the biomass-based CCHP system could improve the ecological footprint of the island, substantially decrease expenditure for the hotel owner, and generate a new source of income for surrounding farmers through biomass selling.