New parameter adjustment with spinal cord stimulation for postherpetic neuralgia treatment: A case report and literature review

Tang, Yuru; Wang, Rui; Gao, Xiao; Deng-bin, AI

doi:10.1016/j.dsi.2018.07.004

Cited by 2 publications

(1 citation statement)

References 23 publications

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“…Te authors tried diferent parameters of SCS, initially, the high frequency of 360 Hz was chosen, but then the stimulator was programmed at 40 Hz. Within 7 days there was a remarkable drop in neuropathic pain from 9 points to 2 points on VAS [21]. Lerman et al also presented a case of subcutaneous implantation of the peripheral nerve stimulator that resulted in an 80% pain regression with high-frequency programs of 1200 Hz and 100 Hz in a 52-year-old man with drugresistant postherpetic neuralgia in the area of the frst branch of the trigeminal nerve [31].…”

Section: High-frequency Spinal Cord Stimulationmentioning

confidence: 99%

The Effectiveness of Various Types of Electrical Stimulation of the Spinal Cord for Chronic Pain in Patients with Postherpetic Neuralgia: A Literature Review

Isagulyan

Tkachenko

Semenov

et al. 2023

Pain Research and Management

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Introduction. Postherpetic neuralgia (PHN) is a severe condition that remains a challenge to treat. Spinal cord stimulation (SCS) is used in cases of insufficient efficacy of conservative treatment. However, in contrast to many other neuropathic pain syndromes, there is a huge problem in reaching long-term stable pain relief in patients with PHN using conventional tonic SCS. The objective of this article was to present a review of the current management strategies of PHN, their efficacy, and safety. Materials and Methods. We searched for articles containing the keywords “spinal cord stimulation AND postherpetic neuralgia,” “high-frequency stimulation AND postherpetic neuralgia,” “burst stimulation AND postherpetic neuralgia” and “dorsal root ganglion stimulation AND postherpetic neuralgia” in Pubmed, Web of Science, and Scopus databases. The search was limited to human studies published in the English language. There were no publication period limitations. Bibliographies and references of selected publications on neurostimulation for PHN were further manually screened. The full text of each article was studied once the abstract was analyzed by the searching reviewer and found appropriate. The initial search yielded 115 articles. Initial screening based on abstract and title allowed us to exclude 29 articles (letters, editorials, and conference abstracts). The full-text analysis allowed us to exclude another 74 articles (fundamental research articles, research utilizing animal subjects, and systemic and nonsystemic reviews) and results of PHN treatment presented with other conditions, leaving 12 articles for the final bibliography. Results. 12 articles reporting on the treatment of 134 patients with PHN were analyzed, with a disproportionally large amount of traditional SCS treatment than that to alternative SCS: DRGS (13 patients), burst SCS (1 patient), and high-frequency SCS (2 patients). Long-term pain relief was achieved in 91 patients (67.9%). The mean VAS score improvement was 61.4% with a mean follow-up time of 12.85 months. Although the number of patients in alternative SCS studies was very limited, almost all of them showed good responses to therapy with more than 50% VAS improvement and reduction of analgesic dosage. The article contains a review analysis of 12 articles concerning the current methods of treatment for postherpetic neuralgia including conservative treatment, spinal cord stimulation, and novel neuromodulation strategies. Available information on the pathophysiology of PHN and the effect or stimulation on its course, together with a number of technical nuances concerning various types of neurostimulation are also elucidated in this article. A number of alternative invasive treatments of PHN are also discussed. Conclusions. Spinal cord stimulation is an established treatment option for patients with pharmacologically resistant PHN. High-frequency stimulation, burst stimulation, and dorsal root ganglion stimulation are promising options in the management of PHN due to the absence of paresthesias which can be painful for patients with PHN. But more research is still required to recommend the widespread use of these new methods.

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Section: High-frequency Spinal Cord Stimulationmentioning

confidence: 99%

The Effectiveness of Various Types of Electrical Stimulation of the Spinal Cord for Chronic Pain in Patients with Postherpetic Neuralgia: A Literature Review

Isagulyan

Tkachenko

Semenov

et al. 2023

Pain Research and Management

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Effects of central nervous system electrical stimulation on non-neuronal cells

Williams

Kushwah²,

Dhawan³

et al. 2022

Front. Neurosci.

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Over the past few decades, much progress has been made in the clinical use of electrical stimulation of the central nervous system (CNS) to treat an ever-growing number of conditions from Parkinson’s disease (PD) to epilepsy as well as for sensory restoration and many other applications. However, little is known about the effects of microstimulation at the cellular level. Most of the existing research focuses on the effects of electrical stimulation on neurons. Other cells of the CNS such as microglia, astrocytes, oligodendrocytes, and vascular endothelial cells have been understudied in terms of their response to stimulation. The varied and critical functions of these cell types are now beginning to be better understood, and their vital roles in brain function in both health and disease are becoming better appreciated. To shed light on the importance of the way electrical stimulation as distinct from device implantation impacts non-neuronal cell types, this review will first summarize common stimulation modalities from the perspective of device design and stimulation parameters and how these different parameters have an impact on the physiological response. Following this, what is known about the responses of different cell types to different stimulation modalities will be summarized, drawing on findings from both clinical studies as well as clinically relevant animal models and in vitro systems.

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New parameter adjustment with spinal cord stimulation for postherpetic neuralgia treatment: A case report and literature review

Cited by 2 publications

References 23 publications

The Effectiveness of Various Types of Electrical Stimulation of the Spinal Cord for Chronic Pain in Patients with Postherpetic Neuralgia: A Literature Review

The Effectiveness of Various Types of Electrical Stimulation of the Spinal Cord for Chronic Pain in Patients with Postherpetic Neuralgia: A Literature Review

Effects of central nervous system electrical stimulation on non-neuronal cells

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