IntroductionApplication of geographical information systems (GIS) and remote sensing (RS) in veterinary and human medical sciences, particularly in veterinary and human parasitology, is rapidly advancing. During the past 10-20 years the publication of original research articles and reviews in veterinary and human health with an emphasis on GIS and/or RS has followed an exponential trend (Hendrickx et al., 2004). In addition, recent GIS/RS symposia organized at national and international conferences, and several thematic issues on this topic published in the peer-reviewed international literature (e.g. special theme issues in Advances in Parasitology in 2000and Parassitologia in 2005) demonstrate the wide array of applications and benefits of these tools (Cringoli et al., 2005b). Furthermore, the raised interest about these new technologies is testified by the publication of thematic books pertaining GIS and RS, as well as international peer-reviewed journals, including the current launch of Geospatial Health.The establishment and maintenance of websites as a platform for sharing data, exchanging opinions, experiences and expertise on GIS and RS with an emphasis on animal and public health is also worth mentioning (e.g.http://www.gnosisgis.org; http:// www.gisvet.org).In this review, we first summarize general aspects of GIS and RS, and emphasize the most important applications of these tools in veterinary parasitology, including recent advances in territorial sampling. Disease mapping, spatial statistics, including Bayesian inference, ecological analyses and epidemiological surveillance are summarized in the next section and illustrated with a set of figures. Finally, a set of conclusions is put forward. Abstract. Over the past 10-15 years, significant advances have been made in the development and application of geographical information systems (GIS) and remote sensing (RS). In veterinary sciences, particularly in veterinary parasitology, GIS and RS offer powerful means for disease mapping, ecological analysis and epidemiological surveillance and have become indispensable tools for processing, analysing and visualising spatial data. They can also significantly assist with the assessment of the distribution of health-relevant environmental factors via interpolation and modelling. In this review, we first summarize general aspects of GIS and RS, and emphasize the most important applications of these tools in veterinary parasitology, including recent advances in territorial sampling. Disease mapping, spatial statistics, including Bayesian inference, ecological analyses and epidemiological surveillance are summarized in the next section and illustrated with a set of figures. Finally, a set of conclusions is put forward.