New porcine coronavirus?

Coronaviridae, pathogenetic and clinical aspects: An update

“…In 1986 a variant of TGEV was isolated in Belgium [14] and Great Britain [15]. As it causes a respiratory infection and does not replicate in the enteric tract, it was named "Respiratory Variant" of TGEV [16] and recently "Porcine respiratory coronavirus".…”

Experimental infection of pigs with the porcine respiratory coronavirus (PRCV): measure of viral excretion

“…Respiratory disorders due to viruses are the main problems recorded in areas of intensive porcine production. Common causes of the disease includes pseudorabies virus (PRV), influenza viruses and the porcine respiratory coronavirus (PRCV), the latter being first detected in different European countries in 1983-1984 (Brown et al, 1986;Duret et al, 1988;Pensaert et al, 1986). Serological studies have demonstrated a close relationship between PRCV and transmissible gastroenteritis virus (TGEV) with the viruses being distinguished from each other only by the use of monoclonal antibodies (Laude et al, 1988;Garwes et al, 1988).…”

“…No conclusion could be made concerning the genomic modification (s) controlling the phenotypic difference observed between the viruses, namely the impaired multiplication of PRCV in the digestive tract. Until now, great attention has been given to clinical disorders induced by PRCV in the field (Jestin et al, 1987;Brown and Cartwright, 1986) and under experimental conditions (Vannier, 1990;Pensaert et al, 1986;O'Toole et al, 1989), but nothing is known about excretion and airborne transmission of the virus. In order to better understand that aspect of the epidemiology of PRCV, we studied excretion of the virus in pigs experimentally infected with the virus.…”

Sequence comparison of the 5' end of mRNA 3 from transmissible gastroenteritis virus and porcine respiratory coronavirus

“…The virus does not cause diarrhoea and essentially replicates only in the respiratory tract and not in the gastrointestinal tract, with little or no clinical signs (Pensaert et al, 1986;Pensaert, 1989;Cox et al, 1990). The causative agent, isolated in Belgium (Pensaert et al, 1986) and in Britain (Brown & Cartwright, 1986), was identified as a coronavirus and named porcine respiratory coronavirus (PRCV). The serological response in pigs to infection with PRCV could not be distinguished from TGEV by available diagnostic tests.…”