New possibilities for surgical treatment of borderline burns using biological wound coverings

Abstract

Objective: selection of optimal biological wound coverings for the treatment of patients with borderline burns. Material and methods. The results of treatment of 30 patients aged 28-58 years were analyzed. All patients were diagnosed with second degree burn wounds of varying localization and area from 5 to 20% (according to International Classification of Diseases 10th Revision). Of these, 13 (43%) patients in group I (age 48 [39; 54] years) underwent surgical removal of necrosis, and ChitoPran® biological wound dressings were applied to the wounds. The remaining 17 (56%) patients in group II (age 42 [28; 58] years) also underwent early surgical treatment, but the grafts were covered with synthetic Voskopran™ wound coverings. Results. In group I, where the biological wound coating ChitoPran® was used, the epithelialization period was 10 (9.0; 10.0) days. In group II, where the synthetic wound coating Voskopran™ was used, the epithelialization period was 12 (11.0; 13.0) days (p=0.031). The data obtained show that biological wound coatings ChitoPran® demonstrate an advantage in accelerating the timing of wound epithelization compared with synthetic wound coatings Voskopran™. In group I, the duration of hospitalization was 10.5 (10.0; 11.0) days, for group II — 11.5 (10.0; 12.0) days (p=0.048). Conclusion. A comparative assessment of the effectiveness of biological wound coverings in the treatment of patients with borderline burns showed that, in contrast to the synthetic wound covering Voskopran™, the use of the biological wound covering ChitoPran® provides favorable conditions for regeneration, due to which the period of epithelization of wounds was reduced by an average of 1-2 days, and hospitalization time is on average up to 2 days.