New Post-Imaging Software Provides Fast and Accurate Volume Data from CTA Surveillance after Endovascular Aneurysm Repair

Yeung, Kay K.; Laan, Maarten J. van der; Wever, Jan J.; Waes, P. F. G. M. van; Blankensteijn, Jan D.

doi:10.1177/152660280301000507

Cited by 13 publications

(15 citation statements)

References 11 publications

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“…This greater distribution may equate to a greater ability to detect which AAAs have progressed over time. Total AAA volume analysis has been successfully employed in patients following endoluminal AAA repair 103,105–107. For example, Wever et al (2000) discovered that one third of patients had significant volume change without maximal orthogonal diameter change 106.…”

Section: 0 Current Diagnosis Of Aaamentioning

confidence: 99%

Diagnosis and Monitoring of Abdominal Aortic Aneurysm: Current Status and Future Prospects

Moxon

Parr²,

Emeto³

et al. 2010

Current Problems in Cardiology

130

148

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Abdominal aortic aneurysm (AAA) remains an important cause of morbidity and mortality in elderly men, and prevalence is predicted to increase in parallel with a global ageing population. AAA is commonly asymptomatic, and in the absence of routine screening, diagnosis is usually incidental when imaging to assess unrelated medical complaints. In the absence of approved diagnostic and prognostic markers, AAAs are monitored conservatively via medical imaging until aortic diameter approaches 50-55mm and surgical repair is performed. There is currently significant interest in identifying molecular markers of diagnostic and prognostic value for AAA. Here we outline the current guidelines for AAA management, and discuss modern scientific techniques currently employed to identify improved diagnostic and prognostic markers. KeywordsAbdominal aortic aneurysm; diagnosis; prognosis; biomarker INTRODUCTIONAn abdominal aortic aneurysm (AAA) is a dilation of the infra-renal aorta, which appears to result from chronic weakening of the arterial wall, increasing the risk of fatal rupture.1 -3 AAA is also associated with an increased risk of other major cardiovascular events in aneurysmal patients. For example the UK small aneurysm trial (UKSAT), demonstrated that only 16% of deaths in patients with 40-55mm AAAs was related to AAA repair or rupture while ~50% were due to other cardiovascular causes (mainly myocardial infarction and stroke).4 Publisher's Disclaimer: This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. NIH Public Access AAA pathologyMacroscopically, an AAA can be considered a dilatation of the infrarenal aorta, giving rise to a permanent vessel diameter >30mm (typical abdominal aortic diameter ranges from 15 to 25mm). 23-27 AAA vessel dilation is commonly progressive, and is often accompanied by the formation of a laminated, non-occlusive, intraluminal thrombus.28 -29 Thrombus size and location varies between patients, and the arterial wall may be partially or completely covered by the thrombus ( Figure 1A and B). 30 The thrombus remains in permanent contact with circulating blood and is continually remodeled, 31,32 and thrombus size increases in parallel with aortic dilation. Due to constant remodeling the thrombus is a laminated structure comprising a red blood cell-rich luminal layer in contact with the flowing blood, progressing to a brown fibrinolysed layer at the aortic wall. 29 Localised hypoxia has been demonstrated in regions of the aorta covered by the thrombus and this has been suggested to contribute to physiological stresses within the arterial wall. 33 Similar to other vascular dise...

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Section: 0 Current Diagnosis Of Aaamentioning

confidence: 99%

Diagnosis and Monitoring of Abdominal Aortic Aneurysm: Current Status and Future Prospects

Moxon

Parr²,

Emeto³

et al. 2010

Current Problems in Cardiology

130

148

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“…10,11 The mean difference between the volume measurement with the manual method on the EasyVision workstation and the true volume of the phantom was 20.7 mL (20.4%), with a RC of 2.2 mL (1.3%). 10 In this study by Yeung et al, 10 the Vitrea workstation was compared to the EasyVision workstation. The Vitrea measurements were made by drawing aortic contour lines on 5 to 8 axial slices, which were then interpolated to the total aneurysm volume.…”

Section: Discussionmentioning

confidence: 97%

“…The purpose of this study was to compare intra-and interobserver variability data of a previously validated manual segmentation method and a semi-automatic method that uses CLL reconstructions. 10,11 METHODS Volume measurements were performed on 20 abdominal CTA datasets (10 pre and 10 post EVAR), which were randomly selected from the clinical database of our institution. The datasets were from 14 AAA patients (12 men; mean age 70 years, range 57-87); in 6 patients, a pre-and a postoperative scan were selected.…”

mentioning

confidence: 99%

Intra- and Interobserver Variability of Aortic Aneurysm Volume Measurement With Fast CTA Postprocessing Software

Prehn¹,

Wal²,

Vincken

et al. 2008

Journal of Endovascular Therapy

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The semi-automatic method showed good intra- and interobserver variability for volume measurements of aortic aneurysms before and after EVAR. Volume measurements with the semi-automatic method correspond to measurements with the standard method. Sophisticated and fast postprocessing software may facilitate acceptance and clinical application of volume measurements in daily practice. The cutoff of 5% for relevant volume changes during follow-up, as advised in the reporting standards for EVAR, is sustained.

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“…The analyzed workstation has already proven to be effective for automatic and rapid estimation of the volume of abdominal aortic aneurysms [15], for detection of colorectal polyps with MSCT [16], and for 3D volume rendering for accurate measurements for dental implant placement [17]. Our results show that automatic vessel detection for display of the coronary vessels on curved MPRs and on planes orthogonal to the vessel is feasible with the workstation, while reducing the time required to create reformations by a factor of approximately two.…”

Section: Discussionmentioning

confidence: 99%

Multislice CT Coronary Angiography: Evaluation of an Automatic Vessel Detection Tool

Dewey

Schnapauff²,

Laule³

et al. 2004

Rofo Fortschr Geb Rontgenstr N

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New Post-Imaging Software Provides Fast and Accurate Volume Data from CTA Surveillance after Endovascular Aneurysm Repair

Abstract: The Vitrea workstation provides fast and accurate volume data from spiral CTA follow-up of endovascular aneurysm repair. This software may enhance the acceptability of volume surveillance in daily practice.

Cited by 13 publications

References 11 publications

Diagnosis and Monitoring of Abdominal Aortic Aneurysm: Current Status and Future Prospects

Diagnosis and Monitoring of Abdominal Aortic Aneurysm: Current Status and Future Prospects

Intra- and Interobserver Variability of Aortic Aneurysm Volume Measurement With Fast CTA Postprocessing Software

Multislice CT Coronary Angiography: Evaluation of an Automatic Vessel Detection Tool

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