New progress in CT and MRI examination and diagnosis of small intestinal tumors

Miao, Fei; Wang, Mingliang; Tang, Yonghua

doi:10.4251/wjgo.v2.i5.222

Cited by 14 publications

(15 citation statements)

References 28 publications

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“…Currently, magnetic resonance enterography (MRE), CT colonography (CTC) and wireless capsule endoscopy (WCE) have all been shown to be effective in reaching the diagnosis. 7 CTC and MRE are able to detect mucosal changes, whilst offering good sensitivity to any metastatic changes, 8,9 as well as information with regard to any metastases. WCE on the other hand is superior in visualising small superficial lesions.…”

Section: Discussionmentioning

confidence: 99%

Leiomyosarcoma of the small bowel: Report of a case and review of the literature

Luis

Ejtehadi

Howlett

et al. 2015

International Journal of Surgery Case Reports

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HighlightsCase of 83 year old gentleman with chronic anaemia and ominous GI symptoms but unremarkable initial examination and investigations.Leiomyosarcomas of the small bowel is extremely rare and can be differentiated from gastrointestinal stromal tumours by immunohistochemical methods.Imaging in the form of MRE, CT colonography or WCE are crucial when faced with a differential diagnosis of small bowel malignancy.

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Section: Discussionmentioning

confidence: 99%

Leiomyosarcoma of the small bowel: Report of a case and review of the literature

Luis

Ejtehadi

Howlett

et al. 2015

International Journal of Surgery Case Reports

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“…Several reports have evaluated the advantages and disadvantages of CT and MRI for the diagnosis of SBTs. 2 , 39 , 40 Finally, the number of included patients was relatively small, indicating the need for studies in larger numbers of patients with SBTs.…”

Section: Discussionmentioning

confidence: 99%

“… 4 The clinical diagnosis of SBTs has been difficult because of the lack of specific clinical symptoms and effective diagnostic approaches. 2 , 3 , 5 , 6 Primary and secondary SBTs are sometimes incidentally diagnosed by obscure GI bleeding and/or acute abdominal pain. 6 , 8 …”

Section: Introductionmentioning

confidence: 99%

Usefulness of Ultrasonography for Diagnosis of Small Bowel Tumors

Fujita¹,

Manabe²,

Honda³

et al. 2015

Medicine

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Ultrasonography is a standard, noninvasive modality used to evaluate patients with gastrointestinal diseases. This study assessed the usefulness of ultrasonography in the detection of small bowel tumors.This study enrolled 558 consecutive patients (295 males, 263 females; mean age 71.1 years) who underwent ultrasonography before capsule endoscopy and/or balloon-assisted endoscopy. Ultrasonographic detection of small bowel tumors was compared with detection by capsule endoscopy and/or balloon-assisted endoscopy. In addition, factors affecting small bowel tumor detection by ultrasonography and clinical characteristics of patients with small bowel tumors undetected by ultrasonography were evaluated.Ninety-seven tumors (52 benign, 45 malignant) detected by capsule endoscopy and/or balloon-assisted endoscopy were retrospectively analyzed. The sensitivity and specificity of ultrasonography in the detection of small bowel tumors were 50.5% (47/93) and 100% (465/465), respectively. If we restricted patients to those with a tumor >20 mm in size, its detection ratio would become higher (91.7%): the ratio of submucosal tumor >20 mm in size was 85.7% (6/7) and that of partial and circumferential ulcerative tumors >20 mm in size was 96.9% (31/32), respectively. Small bowel tumors detected by ultrasonography (mean 33.2 mm) were significantly larger than those undetected by ultrasonography (mean 8.7 mm). The percentage of small bowel tumors located in the ileum detected by ultrasonography (70.6%) was significantly higher than those undetected by ultrasonography (29.4%). Of the 46 small bowel tumors undetected by ultrasonography, 42 (91.3%) were benign tumors with good clinical prognosis.Ultrasonography is a useful modality for detecting larger small bowel tumors and ulcerative lesions. Ultrasonography should be considered a first-line modality for patients suspected of having small bowel tumors, because most small bowel tumors undetected by ultrasonography were benign tumors with good clinical prognosis.

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“…In addition, with regard to the rate of detection of neoplastic lesions by CE, an existing report used CE on 443 subjects, which detected small bowel tumors in 11 of the subjects (2.4%) [ 40 ]. In our facility, the number of small bowel tumors detected was as high as 6/98 (6.1%) and small intestine cancers, which accounted for 33–47% of primary small intestine tumors [ 4 , 41 ], and malignant lymphomas, which accounted for 10–30% of malignant tumors of the small intestine [ 42 ], were not included in the details regarding the small bowel tumor lesions that were detected. Thus, the cases that were selected in our study may have been biased.…”

Section: Discussionmentioning

confidence: 99%

Beneficial Effects of Combining Computed Tomography Enteroclysis/Enterography with Capsule Endoscopy for Screening Tumor Lesions in the Small Intestine

Shibata

Hashimoto

Shimizu

et al. 2015

Gastroenterology Research and Practice

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Aim. To compare the efficacy of using computed tomography enteroclysis/enterography (CTE), capsule endoscopy (CE), and CTE with CE for diagnosing tumor lesions in the small intestine. Materials and Methods. We included 98 patients who underwent CE during the observation period and were subjected to CTE at our hospital from April 2008 to May 2014. Results. CTE had a significantly higher sensitivity than CE (84.6% versus 46.2%, P = 0.039), but there were no significant differences in specificity, positive or negative predictive values, or diagnostic accuracy rates. The sensitivity of CTE/CE was 100%, again significantly higher than that of CE (P = 0.002). The difference in specificity between CTE/CE and CE was not significant, but there were significant differences in positive predictive values (100% for CTE/CE versus 66.7% for CE, P = 0.012), negative predictive values (100% versus 92.1%, P = 0.008), and diagnostic accuracy rate (100% versus 89.8%, P = 0.001). The diagnostic accuracy rate was also significantly higher in CTE/CE versus CTE (100% versus 95.9%, P = 0.043). Conclusion. Our findings suggested that a combination of CTE and CE was useful for screening tumor lesions in the small intestine. This trial is registered with number UMIN000016154.

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New progress in CT and MRI examination and diagnosis of small intestinal tumors

Cited by 14 publications

References 28 publications

Leiomyosarcoma of the small bowel: Report of a case and review of the literature

Leiomyosarcoma of the small bowel: Report of a case and review of the literature

Usefulness of Ultrasonography for Diagnosis of Small Bowel Tumors

Beneficial Effects of Combining Computed Tomography Enteroclysis/Enterography with Capsule Endoscopy for Screening Tumor Lesions in the Small Intestine

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