New role for astroglia in learning: Formation of muscle memory

Hassanpoor, Hossein; Fallah, Ali; Raza, Mohsin

doi:10.1016/j.mehy.2012.08.025

Cited by 17 publications

(9 citation statements)

References 26 publications

(27 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Taken together, training in the 'wrong' sensory context (that will abruptly change at the time for surgery) [54] together with a possible lesser central nervous ability to adapt, may account for the worse postural outcomes for the group that did not receive the PREHAB protocol. That being stated, a familiarity with the exercises before surgery is also important, since beneficial aspects of training after a manifest unilateral loss is beyond question, and although the sensory weighting might be affected, the muscle memory for the exercises are important in postsurgical rehabilitation [19].…”

Section: Discussionmentioning

confidence: 99%

PREHAB vs. REHAB – presurgical treatment in vestibular schwannoma surgery enhances recovery of postural control better than postoperative rehabilitation: Retrospective case series

Tjernström

Fransson

Kahlon

et al. 2018

VES

View full text Add to dashboard Cite

By separating the sensory loss (through intratympanic gentamicin, that ablates the remaining vestibular function) from the intracranial surgical trauma, the postural control system benefited from a better short-term (adaptation) and long-term (habituation) recovery, when experiencing a postural challenge or resolving a sensory conflict. The benefits could be attributed to; active and continuous motor learning as the vestibular function slowly attenuates; no concomitant central nervous dysfunction due to effects from neurosurgery, thus allowing time for a separate unimpeded recovery process with more limited challenges and objectives; and the initiation and certain progression of sensory reweighting processes allowed prior to surgery. In contrast, worse compensation could be due to; immobilization from nausea after surgery, harmful amount of stress and cognitive dysfunction from the combination of surgical and sensory trauma and an abrupt vestibular deafferentation and its consequences on sensory reweighting.

show abstract

Section: Discussionmentioning

confidence: 99%

PREHAB vs. REHAB – presurgical treatment in vestibular schwannoma surgery enhances recovery of postural control better than postoperative rehabilitation: Retrospective case series

Tjernström

Fransson

Kahlon

et al. 2018

VES

View full text Add to dashboard Cite

show abstract

“…Astrocytic glial cells are the most numerous cell type within the central nervous system (CNS) and peripheral nervous system (PNS). The function of these cell models regulates neuronal signaling, protects neurons from oxidative damage, and determines the fate of endogenous neural precursors. , During the development of glioblastoma multiforme (GBM), tumor-associated astrocytic glial cells directly contact GBM cells, which activate astrocytes to form reactive astrocytes, facilitating tumor progression, proliferation, and migration through multiple well-understood signaling pathways. − Diffuse gliomas are categorized histologically as astrocytomas, oligodendrogliomas, or oligoastrocytomas. Astrocytomas are pathologically graded in keeping with the World Health Organization (WHO) as grade II (low grade), grade III (anaplastic astrocytoma), or grade IV (high grade, GBM) .…”

Section: Discussionmentioning

confidence: 99%

Investigation of Cytotoxicity and Oxidative Stress Induced by the Pyrethroid Bioallethrin in Human Glioblastoma Cells: The Protective Effect of Vitamin E (VE) and Its Underlying Mechanism

Lin

Chen

Liang

2022

Chem. Res. Toxicol.

View full text Add to dashboard Cite

Bioallethrin belongs to the family of pyrethroid insecticides. Previous studies have shown that bioallethrin affected the function of muscarinic receptor and subsequently induced neurotoxicity in different brain models. Reactive oxygen species (ROS) are generated in the metabolic course of the human body, which can cause human damage when overactivated. However, whether bioallethrin evokes cytotoxicity through ROS signaling and whether the antioxidant Vitamin E (VE) protects these cytotoxic responses in human glial cell model are still elusive. This study investigated the effect of bioallethrin on cytotoxicity through ROS signaling and evaluated the protective effect of the antioxidant VE in DBTRG-05MG human glioblastoma cells. The cell counting kit-8 (CCK-8) was used to measure cell viability. Intracellular ROS and glutathione (GSH) levels were measured by a cellular assay kit. The levels of apoptosis- and antioxidant-related protein were analyzed by Western blotting. In DBTRG-05MG cells, bioallethrin (25–75 μM) concentration-dependently induced cytotoxicity by increasing ROS productions, decreasing GSH contents, and regulating protein expressions related to apoptosis or antioxidation. Furthermore, these cytotoxic effects were partially reversed by VE (20 μM) pretreatment. Together, VE partially lessened bioallethrin-induced apoptosis through oxidative stress in DBTRG-05MG cells. The data assist us in identifying the toxicological mechanism of bioallethrin and offer future development of the antioxidant VE to reduce brain damage caused by bioallethrin.

show abstract

“…Wing and Kristofferson proposed a model for memory-paced tapping pointing to combined contributions of perceptual and motor-based working memory (Wing and Kristofferson 1973). The importance of motor-engagement for rhythm perception has been substantiated by a wealth of neuroimaging studies, demonstrating the involvement of motor related regions – both cortical and subcortical – in timing- and rhythm-related processes, even in the absence of overt motion (Ivry 1996; Penhune et al 1998; Lustig et al 2005; Grahn and Brett 2007; Hassanpoor et al 2012; Marvel et al 2020). There are also growing indications that motor movement can directly affect auditory perception, particularly when stimuli are rhythmic or temporally predictable (Thaut et al 2001; Schroeder et al 2010; Chemin et al 2014; Park et al 2015; Morillon and Baillet 2017; Rimmele et al 2018).…”

Section: Discussionmentioning

confidence: 99%

Memory-paced tapping to auditory rhythms: Effects of rate, speech and motor-engagement

Amrani

Golumbic

2021

Preprint

View full text Add to dashboard Cite

Humans have a near-automatic tendency to entrain their motor actions to rhythms in the environment. Entrainment is hypothesized to play an important role in processing naturalistic stimuli, such as speech and music, which have intrinsically rhythmic properties. Here we studied two facets of entraining one's rhythmic motor actions to an external stimulus: (1) synchronized finger tapping to auditory rhythmic stimuli, and (2) memory-paced reproduction of a previously heard rhythm. Using modifications of the Synchronization-Continuation tapping paradigm, we studied how these two rhythmic behaviours were affected by different stimulus and task features. We tested synchronization and memory-paced tapping for a broad range of rates, from sub-second to supra-second, both for isochronous tone-sequences and for rhythmic speech stimuli (counting from one to ten), which are more ecological yet less strictly isochronous. We also asked what role motor engagement plays in forming a stable internal representation for rhythms and guiding memory-paced tapping. Results show that individuals can flexibly synchronize their motor actions to a very broad range of rhythms. However, this flexibility does not extend to memory-paced tapping, which is accurate only in a narrower range of rates, around ~1.5Hz. This pattern suggests that intrinsic rhythmic-defaults in the auditory/motor systems influence the internal representation of rhythms, in the absence of an external pace-maker. Interestingly, memory-paced tapping for speech rhythms and simple tones shared similar 'optimal rates', although with reduced accuracy, suggesting that internal constraints on rhythmic entrainment may generalize to more ecological stimuli. Last, active synchronization led to more accurate memory-paced tapping vs. passive listening, which emphasizes the importance of action-perception interactions in forming stable entrainment to external rhythms.

show abstract

New role for astroglia in learning: Formation of muscle memory

Cited by 17 publications

References 26 publications

PREHAB vs. REHAB – presurgical treatment in vestibular schwannoma surgery enhances recovery of postural control better than postoperative rehabilitation: Retrospective case series

PREHAB vs. REHAB – presurgical treatment in vestibular schwannoma surgery enhances recovery of postural control better than postoperative rehabilitation: Retrospective case series

Investigation of Cytotoxicity and Oxidative Stress Induced by the Pyrethroid Bioallethrin in Human Glioblastoma Cells: The Protective Effect of Vitamin E (VE) and Its Underlying Mechanism

Memory-paced tapping to auditory rhythms: Effects of rate, speech and motor-engagement

Contact Info

Product

Resources

About