New routes for the synthesis of unsymmetrical diarylselenides: Effect of heat, light and ultrasound

Understanding flow chemistry for the production of active pharmaceutical ingredients

“…The leaching in case of supported catalysis can be arrested by improving metal support interaction with deliberately developed surface defects ( Burange et al., 2016 ) and among others ( Burange et al., 2021 ). Coupling reactions over non-precious metals complexes are also reported in order to reduce the cost of the final catalyst ( Sahani et al., 2018a , 2018b , 2019 ). However, such homogeneous catalysts are difficult to recycle; therefore, there are few attempts on immobilization of them onto solid support ( Collis and Horváth, 2011 ).…”

Metal‐Free Photochemical C−Se Cross‐Coupling of Aryl Halides with Diselenides

“…In recent years, Lee and Liu respectively reported the visible‐light‐promoted synthesis of asymmetric diarylselenoethers from diselenide (Scheme 1c) [8] . Subsequently, Jayaram and co‐workers described a thermally‐assisted photochemical coupling reaction of diphenyldiselenide and phenylhydrazine hydrochloride to construct asymmetric diarylselenoethers [9a] . Other photo‐induced reactions regarding C−Se bond formation were also successively disclosed [9b–c] .…”

Green Synthesis of Diaryl Selenides from Arylboronic Acids and Arylseleninic Acids

“…Very recently, our group found a new method of ipso-selenocyanation of arylboronic acids without base, additive or metal (Scheme 1a). 7 In 2020, the same products were synthesized by electrochemical reaction (Scheme 1b). 8a From selenium powder (Se), selenocyanation was developed efficiently with TMSCN in DMSO (Scheme 1c).…”