New science challenges old notion that mercury dental amalgam is safe

Homme, Kristin G.; Kern, Janet K.; Haley, Boyd E.; Geier, David A.; King, Paul; Sykes, Lisa K.; Geier, Mark R.

doi:10.1007/s10534-013-9700-9

Cited by 54 publications

(45 citation statements)

References 19 publications

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“…Over time, this phase gradually transforms into the b-1 phase, which contains less mercury, and this conversion causes the release of mercury (14). In addition to this sustained mercury release, other factors affecting the release process include dismantling of the filling, wear from mechanical stimuli (chewing, consumption of carbonated drinks, functional movements such as brushing of the teeth, and parafunctional habits such as bruxism), galvanic corrosion, electrochemical corrosion, and oral conditions (temperature, pH level, and negative air pressure) (3,4,15,16). Previous studies have measured the amounts of mercury released due to these factors (5, [17][18][19].…”

Section: Discussionmentioning

confidence: 99%

Ex Vivo Mercury Release from Dental Amalgam after 7.0-T and 1.5-T MRI

Yılmaz

Adışen

2018

Radiology

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Purpose To evaluate ex vivo mercury release from dental amalgam after 7.0-T and 1.5-T MRI. Materials and Methods The authors evaluated 60 caries-free molar or premolar teeth that had been extracted for clinical indications. Two-sided cavities were opened in each tooth and amalgam fillings applied. After 9 days, two groups of 20 randomly selected teeth were placed in 20 mL of artificial saliva immediately followed by 20 minutes of MRI exposure at 1.5 or 7.0 T. A control group of teeth was placed in artificial saliva without undergoing MRI exposure. The teeth were removed from the artificial saliva 24 hours later, and the saliva was analyzed for mercury content by using inductively coupled plasma mass spectrometry. One-way analysis of variance was used to compare the mean mercury values among the three independent groups, and the Tukey test was used for multiple comparisons of the mean values. Results The mean mercury content of the artificial saliva was 673 μg/L ± 179 in the 7.0-T MRI group, 172 μg/L ± 60 in the 1.5-T MRI group, and 141 μg/L ± 152 in the control group. The mercury content in the 7.0-T group was greater than that in both the 1.5-T group (P < .001; 95% confidence interval: 368 μg/L, 633 μg/L) and the control group (P < .001; 95% confidence interval: 416 μg/L, 648 μg/L). There was no statistically significant difference in mercury content between the 1.5-T and control groups (P = .84; 95% confidence interval: -164 μg/L, 110 μg/L). Conclusion In an ex vivo setting, mercury was released from amalgam fillings after exposure to 7.0-T MRI but not 1.5-T MRI.

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Section: Discussionmentioning

confidence: 99%

Ex Vivo Mercury Release from Dental Amalgam after 7.0-T and 1.5-T MRI

Yılmaz

Adışen

2018

Radiology

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“…Exposure to of Hg appeared to increase the level of total testosterone, presumably due to increased levels of the steroid‐binding globulin (SHBG). However, for prolactin, cortisol and TSH, such a relationship was not detected …”

Section: Occupational Exposure To Mercurymentioning

confidence: 88%

Mercury exposure and its effects on fertility and pregnancy outcome

Bjørklund

Chirumbolo

Dadar

et al. 2019

Basic Clin Pharma Tox

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Mercury (Hg), a highly toxic environmental pollutant, shows harmfulness which still represents a big concern for human health, including hazards to fertility and pregnancy outcome. Research has shown that Hg could induce impairments in the reproductive function, cellular deformation of the Leydig cells and the seminiferous tubules, and testicular degeneration as well as abnormal menstrual cycles. Some studies investigated spontaneous abortion and complicated fertility outcome due to occupational Hg exposure. Moreover, there is a relation between inhaled Hg vapour and reproductive outcome. This MiniReview evaluates the hypothesis that exposure to Hg may increase the risk of reduced fertility, spontaneous abortion and congenital deficits or abnormalities.

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“…Literatürde amalgam dolgulardan cıva salınımını artıran bazı durumlar belirtilmiştir. Bunlar mekanik stimülasyon (çiğneme, karbonatlı içecekler, diş fırçalama, bruksizm gibi parafonksiyonel alışkanlıklar), galvanik korozyon, elektrokimyasal korozyon ve ağız ortamındaki değişimlerdir (sıcaklık, pH değeri ve negatif hava basıncı gibi) (11)(12)(13). Baş boyun bölgesini görüntülemek için kullanılan görüntüleme yöntemlerinin dental materyaller ile etkileşimi çalışılan bir konudur (14)(15)(16)(17).…”

Section: İstatistiksel Yöntemunclassified

In-Vitro Representation of Mercury Release from Amalgam Restorations after Cone-Beam Computed Tomographic Imaging

Yılmaz¹

2019

Akd Med J

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ÖZAmaç: Çalışmada amalgam dolgulardan konik ışın demetli bilgisayarlı tomografi (KIBT) ile görüntüleme sonrası oluşacak cıva sızıntısını test etmeyi amaçladık.Gereç ve Yöntemler: Çalışma Kırıkkale Üniversitesi Etik Kurul onayı alınarak yapıldı ve her dişin kullanımı için hastalardan yazılı onam alındı. Çeşitli nedenlerle çekilmiş 40 adet çürüksüz molar ve premolar dişe 2 yüzlü kaviteler açıldı, klinik prosedüre uygun olarak amalgam dolgular yapıldı. Dişler rastgele kontrol ve deney grubu olmak üzere iki gruba ayrıldı. Amalgamın sertleşme süreci tamamlandıktan bir hafta sonra dişler 20ml yapay tükürük (Fusayama solüsyonu) içeren tüpler içerisine kondu. Kontrol grubu 24 saat bekletilirken; deney grubundaki dişler tüpler içerisinde KIBT ile belirli parametrelerde görüntülendi. Görüntülemeyi takip eden 24 saat sonrasında dişler tüplerden çıkarılıp cıva konsantrasyonu için İndüktif Olarak Eşleştirilmiş Plazma -Optik Eisyon Spektrometresi (ICP-OES) ile analize gönderildi.Bulgular: KIBT ile ekspoze edilen amalgam dolgulu dişlerden 24 saat içerisinde yapay tükürüğe salınan cıva miktarı ortalama 0,268±0,197 ppm iken, kontrol grubunda bu değer 0,141±0,152 ppm olarak saptandı.Sonuç: Bu bulgular ışığında, deneysel koşullarda, amalgam dolgulu dişlerde KIBT ile gerçekleştirilen görüntüleme cıva salınımını artırmaktadır diyebiliriz.Anahtar Sözcükler: Amalgam, Cıva, Konik ışın demetli bilgisayarlı tomografi ABSTRACT Objective: In this study, we aimed to evaluate the mercury leakage of from dental amalgam fillings after cone beam computed tomography (CBCT) scan. Material and Methods:This study was approved by the Kırıkkale University Clinical Research Ethics Committee. Written informed consent was obtained from the patients for the use of the extracted teeth in this project. Forty caries-free molar or premolar teeth that had been extracted for clinical indications were used. Two-sided cavities were prepared and amalgam fillings applied to each tooth. One week after amalgam setting process, two groups of 20 randomly selected teeth were placed in 20 mL of artificial saliva. In the experiment group, tubes were immediately exposed with CBCT. The control group was kept under normal conditions. Twenty-four hours later the teeth were removed from the artificial saliva, and the saliva was analyzed for mercury content by using Inductively Coupled Plasma Optical Emission Spectrometry. Results:The amount of mercury released to the artificial saliva was found to be 0.268±0.197 ppm in CBCT group within 24 hours, whereas this value was 0.141±0.152 ppm in the control group. Conclusion:The findings of this study indicated that CBCT imaging of teeth restored with amalgam leads an increase in mercury leakage under experimental conditions.

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New science challenges old notion that mercury dental amalgam is safe

Cited by 54 publications

References 19 publications

Ex Vivo Mercury Release from Dental Amalgam after 7.0-T and 1.5-T MRI

Ex Vivo Mercury Release from Dental Amalgam after 7.0-T and 1.5-T MRI

Mercury exposure and its effects on fertility and pregnancy outcome

In-Vitro Representation of Mercury Release from Amalgam Restorations after Cone-Beam Computed Tomographic Imaging

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