New spectrophotometric method for the quantitative determination of melamine using Mannich reaction

Rima, Jamil; Abourida, Maurice; Xu, Ting; Cho, Il Kyu; Kyriacos, Soula

doi:10.1016/j.jfca.2009.02.010

Cited by 39 publications

(18 citation statements)

References 9 publications

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“…The individual complexing agents did not interfere with the spectrum of the larger complex. This result is consistent with a previous report [14], though the complex was formed among melamine, formaldehyde and uranine rather than the compounds used in this procedure. The absorption spectrum of the Mel-AN-Fd complex was in the range of 220-240 nm and increased with increasing melamine concentrations.…”

Section: Complex Of Mel-an-fdsupporting

confidence: 93%

“…Spectrophotometry is widely used for quantitative analysis because of its common availability in laboratories, the simplicity of spectrophotometric procedures, and for its precision and accuracy. Rima et al [14] reported a spectrophotometric method for detection of melamine in fish samples based on the Mannich reaction [15], which is the reaction of melamine with formaldehyde and uranine. Its complex can absorb the UV radiation at a maximum wavelength of 214 nm.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Simple spectrophotometric method for determination of melamine in liquid milks based on green Mannich reaction

Chansuvarn

Panich

Imyim

2013

Spectrochimica Acta Part A: Molecular and Biomolecular Spectros

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Section: Complex Of Mel-an-fdsupporting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

Simple spectrophotometric method for determination of melamine in liquid milks based on green Mannich reaction

Chansuvarn

Panich

Imyim

2013

Spectrochimica Acta Part A: Molecular and Biomolecular Spectros

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“…A spectrophotometric method based on the Mannich reaction has been reported for melamine detection. The method was tested to determine the level of melamine in a contaminated fish sample with a recovery value and LOD of 97% and 0.063 µg/ml, respectively (Rima et al, 2009). Mauer et al (2009) also described a nondestructive and rapid method to detect melamine in infant formula powder using near-and mid-infrared spectroscopy with an LOD of 1 mg/kg with little to no sample preparation.…”

Section: Other Alternative Methodsmentioning

confidence: 99%

Recent developments in the detection of melamine

Liu¹,

Todd

Zhang³

et al. 2012

J. Zhejiang Univ. Sci. B

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In recent years, there were two reported outbreaks of food borne illness associated with melamine. The presence of melamine and its related compounds in milk, feed, and other foods has resulted in the need for reliable methods for the detection and accurate quantification of this class of contaminants. The sample pretreatment for melamine in a complex matrix usually involves a liquid extraction by a polar solvent, followed by a further clean-up with solid phase extraction. Analyses of melamine and related compounds are commonly carried out by liquid or gas chromatographic methods conjugated with mass spectrometry. Other innovative screening methods, which use antibodies, molecularly imprinted polymers, capillary electrophoresis, and gold nanoparticles, are also used to develop assays and biosensors to melamine. However, many of these methods have been hindered by matrix effects, the solubility of melamine-cyanuric acid complex, and background contamination. This article reviews recent developments for detecting melamine and discusses future directions.

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“…For example, spectrophotometric methods for melamine determination based on the Mannich reaction (Rima, Abourida, et al 2009;Rima, Assaker, et al 2013) and gold nanoparticles Wu et al 2011) have been developed. Nevertheless, these methods require many reagents.…”

Section: Introductionmentioning

confidence: 99%

Determination of Melamine Based on the Formation of an Insoluble Copper-Melamine Complex and Flame Atomic Absorption Spectrometry

2014

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A copper-melamine complex was optimally synthesized by heating excess copper(II), as 50 m mol L À1 copper(II) chloride in 50% (v=v) methanol, and melamine at 80 C. The amount of residual copper(II) in solution after removal of the copper-melamine complex was then measured by flame atomic absorption spectrometry. The concentration of depleted copper was proportional to the concentration of melamine, with a linear calibration curve (melamine concentration against copper absorbance) between 0.5 and 2.5 m mol L À1 (R 2 ¼ 0.9943) and with a limit of detection of 0.50 m mol L À1 . Although external standard calibration provided poor recoveries in fortified fish flesh (40% to 74% for 5 to 10 mg melamine/g), the method of standard addition provided acceptable values (90% to 93%), with a relative standard deviation of 3% to 10%. The results obtained with the standard addition method were in broad agreement with those obtained by high performance liquid chromatography.

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New spectrophotometric method for the quantitative determination of melamine using Mannich reaction

Cited by 39 publications

References 9 publications

Simple spectrophotometric method for determination of melamine in liquid milks based on green Mannich reaction

Simple spectrophotometric method for determination of melamine in liquid milks based on green Mannich reaction

Recent developments in the detection of melamine

Determination of Melamine Based on the Formation of an Insoluble Copper-Melamine Complex and Flame Atomic Absorption Spectrometry

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