“…69 Acyclovir represented the original therapy for HSV, 70,71 but the unwieldy dosing pattern of 5 times a day made compliance an issue. 67 The typical dosing regimen for valacyclovir, however, is 500 mg twice daily for 7 days. 67,68 Once the lesions are fully formed, ruptured, and crusted over, antiviral medications are no longer effective.…”