1995
DOI: 10.1016/0040-4020(95)00829-w
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New synthetic approaches to condensed pyridazinones: alkylpyridazinyl carbonitriles as building blocks for the synthesis of condensed pyridazinones

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Cited by 61 publications
(40 citation statements)
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“…In case of presence excess amount of ammonium acetate pyran-imine, 5, is attacked by NH3 ion yielding acyclic amidine 8 that then cyclizes followed by water elimination to yield compound 9 [11][12][13]. Previously, it was noted in the literature that in some cases pyridazinones 10 are the reaction products ( Figure 2-4) [14][15][16][17][18][19].…”
Section: Synthetic Approaches To Arylazonicotinate Pyrido[32c] Cinmentioning
confidence: 99%
“…In case of presence excess amount of ammonium acetate pyran-imine, 5, is attacked by NH3 ion yielding acyclic amidine 8 that then cyclizes followed by water elimination to yield compound 9 [11][12][13]. Previously, it was noted in the literature that in some cases pyridazinones 10 are the reaction products ( Figure 2-4) [14][15][16][17][18][19].…”
Section: Synthetic Approaches To Arylazonicotinate Pyrido[32c] Cinmentioning
confidence: 99%
“…[8][9][10][11][12][13][14][15] This synthesis can now be conducted by microwave heating in a much shorter time and with higher yields. …”
Section: Synthesis Of Alkyl-substituted Heteroaromatics: a Decade Of mentioning
confidence: 99%
“…Compounds 37 were assigned the E-structure based on 1 H NMR studies which revealed alkene protons with J = 13 Hz. 8,12,[31][32][33] Similarly, compound 7 condensed with DMFDMA to yield the enamine 38. …”
Section: Reactivity Toward Carbon Electrophiles 211 Reactivity Of mentioning
confidence: 99%
“…This methodology has been utilized by Elnagdi et al [1][2][3][4][5][6][7][8] and Döpp et al 9,10 as precursors to thienopyridazines, thienocoumarines and thienoquinolines, which were subsequently reacted with dienophiles yielding benzofused heteroaromatics. The scope of this approach for the synthesis of phthalazines as well as condensed benzopyrans has been defined by the recent work of Döpp and coworkers as well as Elnagdi et al (Scheme 1).…”
Section: Introductionmentioning
confidence: 99%