New Technique for Developing a Proton Range Compensator With Use of a 3-Dimensional Printer

Ju, Sang Gyu; Kim, Min Kyu; Hong, Chae-Seon; Kim, Jin Sung; Han, Youngyih; Choi, Doo Ho; Shin, Dongho; Lee, Se Byeong

doi:10.1016/j.ijrobp.2013.10.024

Cited by 57 publications

(46 citation statements)

References 5 publications

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“…One limitation in the TPS's design of the compensator is the inability to accurately model the dimensions of the drill bit. 4,5,8 The tapering of the drill bit is not taken into account for the plunge technique, which results in underestimation the material removed during the milling process. This could result in discrepancies between the calculated and measured dose.…”

Section: Discussionmentioning

confidence: 99%

“…A high-resolution design is optimal, but the diameter of the drill bit limits the degree of resolution of the compensator design and resultant dose distribution on the distal end of the target. 5,6 In addition, this technique can be very time consuming because the compensator design is very complicated and involves hundreds or thousands of plunge points, making it very challenging to apply to the plunge-drilled RC devices because of the complexity of the device surface. Clinical effectiveness and patient start times can be affected by the time requirements of the plunge technique.…”

Section: Introductionmentioning

confidence: 99%

“…4,8 This error does not cause a large dose deviation in regions of small thickness change, but it is a known source of systematic error. 5 The tapering effect is more pronounced for deeper compensators because more material is removed than accounted for in the compensator design pattern. Ultimately, lack of a true drill bit model could result in calculated and measured dose discrepancies.…”

Section: Introductionmentioning

confidence: 99%

“…Ultimately, lack of a true drill bit model could result in calculated and measured dose discrepancies. 4,5,8 Alternatively, a "smooth" compensator design is available in the TPS. The plunged-depth points must be converted into a 3-dimensional wireframe surface so that the compensator can be milled with a smooth surface.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Is there a clinical benefit with a smooth compensator design compared with a plunged compensator design for passive scattered protons?

et al. 2015

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Is there a clinical benefit with a smooth compensator design compared with a plunged compensator design for passive scattered protons?

et al. 2015

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“…The problem is to reconstruct accurately the structure of the patient's body. Based on our experience in tissue engineering for creating model structures of tissues or whole organs, we reasoned that the precise structure of a bolus could be obtained with three-dimensional (3D) printing technology and produced with a 3D printer (8)(9) .…”

Section: Introductionmentioning

confidence: 99%

Use of a 3D printer to create a bolus for patients undergoing tele-radiotherapy

Łukowiak

Boehlke

Lewocki

et al. 2016

IJRR

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Background: This study describes the possibility of implemen ng threedimensional prin ng technology to create a precise construc on of a planned bolus, based on computed tomography informa on stored in the Digital Imaging and Communica ons in Medicine (DICOM) format file. Materials and Methods: To create the bolus with a 3D printer, we converted data in the DICOM format to the stereolithography (STL) format. In addi on, we produced a paraffin bolus that, tradi onally, is manually placed directly on the pa ent. CT scans were acquired for both boluses, and the images were superimposed onto the pa ent CT scans that were used to design the bolus. The superimposi on of images was performed to compare the fit of the bolus printed on a 3D printer to that of the paraffin bolus made in the tradi onal way. In addi on, for both models, the dose distribu on was simulated. To quan fy the level of matching ML, special formula was used. The ML parameter had a value between 0 and 100%, where 100% indicated a perfect fit between the model and the 3D printed bolus. Results: We verified that 100% of the volume of the 3D printed bolus was located within the contour of the designed model. The ML of the bolus was 94%. For the classical paraffin bolus the ML was only 28%. Conclusion: A bolus printed on a threedimensional printer can faithfully reproduce the structure specified in the project plan. Compared to the classical paraffin bolus, the three-dimensional printed bolus more closely matched the planned model and possessed greater material uniformity.

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Characterizing mechanical and medical imaging properties of polyvinyl chloride‐based tissue‐mimicking materials

Qin

Dyer

et al. 2019

J Applied Clin Med Phys

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Polyvinyl chloride (PVC) is a commonly used tissue‐mimicking material (TMM) for phantom construction using 3D printing technology. PVC‐based TMMs consist of a mixture of PVC powder and dioctyl terephthalate as a softener. In order to allow the clinical use of a PVC‐based phantom use across CT and magnetic resonance imaging (MRI) imaging platforms, we evaluated the mechanical and physical imaging characteristics of ten PVC samples. The samples were made with different PVC‐softener ratios to optimize phantom bioequivalence with physiologic human tissue. Phantom imaging characteristics, including computed tomography (CT) number, MRI relaxation time, and mechanical properties (e.g., Poisson’s ratio and elastic modulus) were quantified. CT number varied over a range of approximately −10 to 110 HU. The relaxation times of the T1‐weighted and T2‐weighted images were 206.81 ± 17.50 and 20.22 ± 5.74 ms, respectively. Tensile testing was performed to evaluate mechanical properties on the three PVC samples that were closest to human tissue. The elastic moduli for these samples ranged 7.000–12.376 MPa, and Poisson’s ratios were 0.604–0.644. After physical and imaging characterization of the various PVC‐based phantoms, we successfully produced a bioequivalent phantom compatible with multimodal imaging platforms for machine calibration and image optimization/benchmarking. By combining PVC with 3D printing technologies, it is possible to construct imaging phantoms simulating human anatomies with tissue equivalency.

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New Technique for Developing a Proton Range Compensator With Use of a 3-Dimensional Printer

Cited by 57 publications

References 5 publications

Is there a clinical benefit with a smooth compensator design compared with a plunged compensator design for passive scattered protons?

Is there a clinical benefit with a smooth compensator design compared with a plunged compensator design for passive scattered protons?

Use of a 3D printer to create a bolus for patients undergoing tele-radiotherapy

Characterizing mechanical and medical imaging properties of polyvinyl chloride‐based tissue‐mimicking materials

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