New Trends in Near-Infrared Fluorophores for Bioimaging

Fluorescent difluoroboron-curcumin analogs: An investigation of the electronic structures and photophysical properties

“…Difluoroboron complexes [1][2][3][4] are attractive targets in research and development of materials for opto-electronic devices [5][6][7] and in biomedicinal applications [3,[8][9][10][11][12][13][14] as they possess electron-accepting properties and strong fluorescence with high quantum yields. However most of the reported difluoroboron complexes show very small stokes shifts and hardly show any solid state fluorescence.…”

Monitoring Criminal Activity through Invisible Fluorescent “Peptide Coding” Taggants

“…This is likely to centre on the substitution of the reagents individual components to suit a specific purpose. For example, the replacement of Rhodamine-110 with a nearinfrared fluorophores may provide enhanced contrast against certain coloured or auto-fluorescent surfaces 13 . The discriminatory power of the taggants code may also be further increased by the use amino acids that feature unnatural modifications.…”

Fluorescent Dyes Used in Polymer Carriers as Imaging Agents in Anticancer Therapy

“…Water-soluble NIR fluorescent labeling probes named KSQ-3 and KSQ-4 substituted with four sulfo groups (-SO 3 -) based on the squaraine backbone exhibited significant fluorescence emission at λ=817 nm. In the presence of BSA which was covalently labeled with KSQ-4 the conjugate showed a strong absorption peak at λ=787 nm and fluorescence emission at λ=812 nm [94,95]. These compounds have satisfying optical characteristics and functionality for bioanalyses thus they enable the development of noninvasive and simple diagnosis techniques.…”