New Trends in Supercritical Fluid Technology and Pressurized Liquids for the Extraction and Recovery of Bioactive Compounds from Agro-Industrial and Marine Food Waste

Fraguela-Meissimilly, Horacio; Bastías-Monte, José Miguel; Vergara, Claudia; Ortiz-Viedma, Jaime; Lemus-Mondaca, Roberto; Flores, Marcos; Toledo-Merma, Pamela; Alcázar-Alay, Sylvia; Gallón-Bedoya, Manuela

doi:10.3390/molecules28114421

Cited by 22 publications

(2 citation statements)

References 152 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…By recognizing the value inherent in the leaves and flowers of Białobrzeskie, Henola, and Tygra, and their potential biological activity, we can maximize the benefits derived from these hemp varieties, enhancing both agricultural practices and human health on multiple fronts. scCO 2 is a commonly used extractant in the pharmaceutical and natural products industries [69][70][71][72][73]. It is a non-toxic, non-flammable, and environmentally friendly solvent [74,75], and it can be easily removed by depressurization and evaporation [76][77][78].…”

Section: Extractionmentioning

confidence: 99%

The Antioxidant and Neuroprotective Potential of Leaves and Inflorescences Extracts of Selected Hemp Varieties Obtained with scCO2

Stasiłowicz-Krzemień,

Sip,

Szulc

et al. 2023

Antioxidants

View full text Add to dashboard Cite

Cannabis sativa, a versatile plant with numerous varieties, holds promising potential for a wide range of biological activity. As raw materials for research, we chose leaves and inflorescences of hemp varieties such as Białobrzeskie, Henola, and Tygra, which are cultivated mainly for their fibers or seeds. The choice of extraction is a key step in obtaining the selected compositions of active compounds from plant material. Bearing in mind the lipophilic nature of cannabinoids, we performed supercritical carbon dioxide (scCO2) extraction at 50 °C under 2000 (a) and 6000 PSI (b). The cannabinoid contents were determined with the use of the HPLC-DAD method. The antioxidant capabilities were assessed through a series of procedures, including the DPPH, ABTS, CUPRAC, and FRAP methods. The capacity to inhibit enzymes that play a role in the progression of neurodegenerative diseases, such as acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and tyrosinase was also studied. The dominant cannabinoids in the extracts were cannabidiol (CBD) and cannabidiolic acid (CBDA). The highest concentration of eight cannabinoids was detected in the Tygra inflorescences extract (b). The most notable antioxidant properties were provided by the Tygra inflorescences extract (b). Nonetheless, it was the Henola inflorescences extract (b) that demonstrated the most efficient inhibition of AChE and BChE, and tyrosinase was inhibited the most significantly by the Białobrzeskie inflorescences extract (b). Multidimensional comparative analysis enrolled all assays and revealed that the Henola inflorescences extract (b) showed the most substantial neuroprotective potential.

show abstract

Section: Extractionmentioning

confidence: 99%

The Antioxidant and Neuroprotective Potential of Leaves and Inflorescences Extracts of Selected Hemp Varieties Obtained with scCO2

Stasiłowicz-Krzemień,

Sip,

Szulc

et al. 2023

Antioxidants

View full text Add to dashboard Cite

show abstract

“…One of the methods to selectively extract bioactive compounds corresponds to the use of supercritical fluids with CO 2 (sc-CO 2 ) [ 17 , 18 ]. Thanks to its non-polar solvent property (sc-CO 2 ), this technique constitutes a productive and clean alternative for the recovery of plant foods and their waste [ 17 , 19 , 20 , 21 , 22 , 23 , 24 , 25 ].…”

Section: Introductionmentioning

confidence: 99%

Obtaining an Oily Ingredient Rich in PUFAS and Tocopherols and a High-Nutritional-Value Flour from Beans (Phaseolus vulgaris L.) by Supercritical CO2 Extraction

Benites-Mena,

Vargas-De-La-Cruz,

Vergara-Valdés

et al. 2023

Foods

Self Cite

View full text Add to dashboard Cite

The objective of this work was to carry out a preliminary study of the fractionation by supercritical CO2 (sc-CO2) extraction of two varieties of Peruvian beans (Phaseolus vulgaris L.), white (WB) and red (RB), to obtain two novel products: an oil rich in essential fatty acids and tocopherols and a defatted flour with high nutritional value and amino acids. The extraction temperature and pressure were optimized using the response surface methodology (RSM) and the extraction kinetics were optimized using the Spline equation. The results revealed that the best extraction conditions for WB and RB were 396.36 Bar, 40.46 °C, with an efficiency of 1.65%; and 391.995 Bar, 44.00 °C, with an efficiency of 1.12%, respectively. The WB and RB oils presented a high degree of polyunsaturation (63.2 and 52.8%, respectively), with oleic, linoleic, and linolenic fatty acids prevailing. Gamma-tocopherol was the predominant antioxidant in both oils. The residual flours (WB and RB) obtained after extraction with sc-CO2 had a high average content of proteins (23%), carbohydrates (61%), and minerals (3%). The limiting amino acids of WB were: Fen + Tyr, Leu, Lys, and in RB, only Leu was limiting. The viscosity of the solutions (20%) of the WB and RB flours mainly adjusted to the Waele’s Ostwald model (r = 0.988). It is concluded that both products (oil and bean flour) obtained in an optimized manner using an eco-friendly technology with sc-CO2 have high nutrient and bioactive component content and can be used in the development of new ingredients and healthy foods of plant origin.

show abstract

Sustainable Point of View: Life Cycle Analysis for Green Extraction Technologies

Aslanbay Guler,

Tepe,

Imamoglu

2024

ChemBioEng Reviews

View full text Add to dashboard Cite

Microalgae have emerged as a promising source of renewable energy and natural bioproducts since they show high biomass productivity, offer carbon dioxide fixation, and exhibit a rich content of compounds. Recent efforts have focused on green extraction technologies that utilize green solvents to further promote sustainability and minimize the environmental impact of the microalgal process. At this point, life cycle analysis (LCA) provides valuable insights into the environmental impacts of specific products and techniques. A comprehensive overview of the life cycle environmental and energy assessments conducted for the extraction of metabolites from microalgae is presented. Special attention is given to using green extraction technologies, i.e., supercritical fluid extraction, pressurized liquid extraction, microwave‐assisted extraction, ultrasound‐assisted extraction, and pulsed‐electric field extraction, and solvents to ensure sustainability. Additionally, the main principles, historical development, tools, and challenges of LCA are discussed. By addressing these aspects, the paper attracts attention to the environmental impacts associated with green extraction techniques for obtaining microalgal metabolites.

show abstract

New Trends in Supercritical Fluid Technology and Pressurized Liquids for the Extraction and Recovery of Bioactive Compounds from Agro-Industrial and Marine Food Waste

Cited by 22 publications

References 152 publications

The Antioxidant and Neuroprotective Potential of Leaves and Inflorescences Extracts of Selected Hemp Varieties Obtained with scCO2

The Antioxidant and Neuroprotective Potential of Leaves and Inflorescences Extracts of Selected Hemp Varieties Obtained with scCO2

Obtaining an Oily Ingredient Rich in PUFAS and Tocopherols and a High-Nutritional-Value Flour from Beans (Phaseolus vulgaris L.) by Supercritical CO2 Extraction

Sustainable Point of View: Life Cycle Analysis for Green Extraction Technologies

Contact Info

Product

Resources

About