New trends in the use of medicinal plants by Algerian diabetic patients, considerations of herb-drug interactions

Chelghoum, Mustapha; Khitri, Walid; Bouzid, Samia; Lakermi, AbdelRahim

doi:10.1016/j.jep.2021.113984

Cited by 13 publications

(8 citation statements)

References 27 publications

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“…Olea europea L., Artemisia herba-alba Asso and Trigonella foenum-graecum L. were the most cited herbals. This is consistent with similar studies (Chetoui et al, 2021;Chelghoum et al, 2021;Skalli et al, 2019;Laadim et al, 2017;Telli et al, 2016;Alami et al, 2015;Jouad et al, 2001), in which the most frequent species used were Trigonella foenum-graecum L., Artemisia herba-alba Asso and Olea europaea L.…”

Section: Results Results Resultssupporting

confidence: 91%

“…According to Suroowan et al (2021), herbal and conventional medicine combination is a potentially dangerous practice leading to perilous Herbal drug interactions and toxicity. In addition, Chelghoum et al (2021) revealed, through several clinical trials, that the anti-diabetic plants had a synergistic effect with oral anti-diabetic agents, which can increase the hypoglycemia of diabetics.…”

Section: Results Results Resultsmentioning

confidence: 99%

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The use of plants in the traditional treatment of diabetes patients: survey in southern Morocco

et al. 2022

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This study was conducted in public healthcare establishments in Guelmim city in south of Morocco to report medicinal plants used in folk medicine to treat diabetes. Three hundred sixty-two informants were interviewed through semi structured interviews. The inventory includes scientiﬁc, popular and common names of the plants, used parts and method of preparation. The survey shows that 24.6% of the patients use these plants. Twenty-seven medicinal plants belonging to seventeen families were inventoried and three species were cited for the first time in the treatment of diabetes in Morocco. Olea europea L., Artemisia herba-alba Asso and Trigonella foenum-graecum L. are the most plant species used to treat diabetes, and the two most cited families are Lamiaceae (5 species) and Apiaceae (4 species). Leaves represented the most utilized part of plants and decoction was the most cited mode of preparation of drugs. The present study highlights the wide variety of herbal remedies used to treat diabetes and the frequency of this use in diabetic patients.

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Section: Results Results Resultssupporting

confidence: 91%

Section: Results Results Resultsmentioning

confidence: 99%

The use of plants in the traditional treatment of diabetes patients: survey in southern Morocco

et al. 2022

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“…Moreover, owing to its ancient history as one of the first cradles of Homo sapiens and civilization in the world, Algeria possesses an important and rich cultural diversity. Although several studies have been undertaken to document the local knowledge regarding the use of medicinal plants to treat different diseases ( Benarba, 2015 ; Benarba et al, 2016 ; Chelghoum et al, 2021 ; Mechaala et al, 2021 ), the Algerian ancestral ethnomedicinal knowledge deserves more ethnobotanical investigations. On the other hand, almost all of these ethnobotanical studies covered one region and therefore the same culture and traditions.…”

Section: Introductionmentioning

confidence: 99%

Medicinal Plants Used by Traditional Healers in Algeria: A Multiregional Ethnobotanical Study

Belhouala

Benarba

2021

Front. Pharmacol.

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Traditional medicine is the cornerstone that boosts scientific research to explore new therapeutic approaches. The study aimed to assess the traditional knowledge and use of medicinal plants to treat various ailments by Algerian traditional healers. Forty traditional healers were face-to-face interviewed in three different Algerian areas (West, Kabylia, and Sahara). The data collected were analyzed using quantitative indices such as fidelity level (FL) and informant consensus factor (FIC). A total of 167 species belonging to 70 families were recorded. Lamiaceae (13%), Asteraceae (13%), Apiaceae (7%), and Rosaceae and Fabaceae (5% each) were the most cited families. The survey revealed that leaves were the most used parts of the plants (29%). Furthermore, decoction (35%), raw (24%), and infusion (19%) were the common modes for the remedies’ preparation. Here, 15% of the total species were newly reported as medicinal plants. Besides, it was reported for the first time a total of 47 new therapeutic uses for 20 known plant species. Of 17 ailments categories, cancer was presented by 44 species, showing the highest FIC of 0.46. Marrubium vulgare L., Artemisia herba-alba Asso., Zingiber officinale Roscoe., and Juniperus phoenicea L. recorded the maximum fidelity value of 100%. Therefore, our study reveals strong ethnomedicinal knowledge shared by local populations living in the three regions studied. The medicinal species with a high FL could be promising candidates for identifying new bioactive molecules.

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“…Herbal medicines and traditional medical practitioners are receiving considerable attention from mainstream health o cials, international medical research, and training institutions. Traditional medicine is estimated used by up to 80% of the population of most developing countries (Chelghoum et al 2021).…”

Section: )mentioning

confidence: 99%

Brazilian spice has anti-diabetic and cardiovascular risk-reducing effects in rats

Miranda,

Pereira,

Paz

et al. 2023

Preprint

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Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia and whose prevalence has been increasing over the years. Diabetes mellitus and atherosclerosis appear to be connected. Natural herbal remedies have proven to be safe and effective alternatives in the treatment of this disease. In Northern Brazil, the species Lippia origanoides Kunth (Verbenaceae), used as a spice, is associated with therapeutic activities, however, its antidiabetic potential lacks studies. This work aimed to evaluate the hypoglycemic and cardiovascular risk-reducing effects of the hydroalcoholic extract of Lippia origanoides Kunth (ELo) in rats with alloxan-induced diabetes (120 mg/kg). The animals received ELo at doses of 75, 150, and 250 mg/kg p.o. for 28 days, and positive control was performed in comparison with Glibenclamide (5 mg/kg). Treatment with ELo at all studied doses showed hypoglycemic and cardiovascular risk-reducing effects. Flavonoids that are directly related to these pharmacological activities were identified in ELo by LC-MS, coupled to a liquid chromatography system. The extract obtained from this spice has a promising action on diabetes with cardioprotection establishing a basis for the development of toxicological studies to validate the plant in traditional medicine and further investigations in humans.

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New trends in the use of medicinal plants by Algerian diabetic patients, considerations of herb-drug interactions

Cited by 13 publications

References 27 publications

The use of plants in the traditional treatment of diabetes patients: survey in southern Morocco

The use of plants in the traditional treatment of diabetes patients: survey in southern Morocco

Medicinal Plants Used by Traditional Healers in Algeria: A Multiregional Ethnobotanical Study

Brazilian spice has anti-diabetic and cardiovascular risk-reducing effects in rats

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