New triterpenoid estersaponins from the root barks of  Pittosporum verticillatum  subsp.  verticillatum  and evaluation of cytotoxicities

Manase, Mahenina Jaovita; Mitaine-Offer, Anne Claire; Miyamoto, Tomofumi; Tanaka, Chiaki; Delemasure, Stéphanie; Dutartre, Patrick; Lacaille‐Dubois, Marie‐Aleth

doi:10.1016/j.fitote.2013.09.002

Cited by 21 publications

(6 citation statements)

References 10 publications

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“…The increasing interest in drug discovery from native medicinal plants has led to many studies on extraction, identification and quantification of bioactive compounds in different species of Pittosporum genus, P. angustifolium included [6][7][8][9][10][11][12][13][14]. Several bioactive compounds have been identified in the crude extracts of P. angustifolium such as triterpenoid saponins in leaves and seeds [7][8][9][10][11], phenolic acids and flavonoids in leaves ( Figure 1) [12], tannins and essential oils in leaves and fruits [11].…”

Section: Introductionmentioning

confidence: 99%

“…Several bioactive compounds have been identified in the crude extracts of P. angustifolium such as triterpenoid saponins in leaves and seeds [7][8][9][10][11], phenolic acids and flavonoids in leaves ( Figure 1) [12], tannins and essential oils in leaves and fruits [11]. Among them, triterpenoid saponins, essential oils and non-tannin polyphenols are reported as main bioactive compounds in the Pittosporum genus [6,13], whereas tannins and alkaloids are minor compounds. There seems to be no alkaloids present in the leaves and fruits of P. angustifolium [11,14].…”

Section: Introductionmentioning

confidence: 99%

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Nutritional Value and Antimicrobial Activity of Pittosporum angustifolium (Gumby Gumby), an Australian Indigenous Plant

Phan

Chaliha

Hong

et al. 2020

Foods

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The indigenous endemic plant P. angustifolium has received attention for nutraceutical and therapeutic applications in Australia. This study investigates for the first time the nutritional value (macro- and micronutrients, minerals, trace elements, polyphenols, carotenoids, saponins and antioxidant capacity) and antimicrobial activity of different botanical parts of P. angustifolium, either collected from the wild or cultivated. Different botanical tissues, geographic location and growing condition (wild vs. cultivated) showed significant (p < 0.05) effects on the tested bioactive compounds, with the leaves having significantly (p < 0.05) higher levels than the stems. Saponins and polyphenols could be identified as the main bioactive compounds in the leaves with up to 4% per dry weight. The extracts of P. angustifolium leaves and stems showed strong antioxidant and antimicrobial activities, especially against Candida albicans. These activities correlated (R2 = 0.64–0.92; p < 0.05) with the levels of polyphenols and saponins, indicating their biologic potential. Findings from this study may provide information for future applications of P. angustifolium in the functional ingredient or nutraceutical industry.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Nutritional Value and Antimicrobial Activity of Pittosporum angustifolium (Gumby Gumby), an Australian Indigenous Plant

Phan

Chaliha

Hong

et al. 2020

Foods

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“…This family is represented in New Caledonia by 45 endemic species belonging to Pittosporum genus. Species from this genus have been widely studied in the world, mainly for terpenoids, saponins, and essential oils ( e.g ., ). In New Caledonia, only Pittosporum pancheri was investigated.…”

Section: Asteridsmentioning

confidence: 97%

New Caledonia: A Hot Spot for Valuable Chemodiversity Part 3: Santalales, Caryophyllales, and Asterids

Coulerie

Poullain

2016

Chemistry & Biodiversity

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The flora of New Caledonia encompasses more than 3000 plant species and an endemism of almost 80%. New Caledonia is even considered as one of the 34 'hot spots' for biodiversity. Considering the current global loss of biodiversity and the fact that several drugs and pesticides become obsolete, there is an urgent need to increase sampling and research on new natural products. In this context, here, we reviewed the chemical knowledge available on New Caledonian native flora from economical perspectives. We expect that a better knowledge of the economic potential of plant chemistry will encourage the plantation of native plants for the development of a sustainable economy which will participate in the conservation of biodiversity. This review is divided into three parts, and the third part which is presented here summarizes the scientific literature related to the chemistry of endemic santalales, caryophyllales, and asterids. We show that the high rate of endemism is correlated with the originality of phytochemicals encountered in New Caledonian plants. A total of 176 original natural compounds have been identified from these plants, whereas many species have not been investigated so far. We also discuss the economic potential of plants and molecules with consideration of their medicinal and industrial perspectives. This review finally highlights several groups, such as Sapotaceae, that are unexplored in New Caledonia despite the high chemical interest in them. These plants are considered to have priority in future chemical investigations.

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“…Table 2 Plant species Reference Anabasis setifera 264 Anemone raddeana 265 Anemone taipaiensis 266,267 Aralia elata 268 Ardisia gigantifolia 269 Astragalus tauricolus 270 Benincasa hispida 271 Calliandra pulcherrima 272 Clematis lasiandra 273 Clematis tangutica 274 Gypsophila trichotoma 275,276 Ilex cornuta 277 Lonicera macranthoides 205 Lysimachia parvifolia 220 Pittospermum verticillatum ssp. verticillatum 278 Pulsatilla chinensis 279 …”

Section: Please Do Not Adjust Marginsmentioning

confidence: 99%

Triterpenoids

Hill

Connolly

2017

Nat. Prod. Rep.

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New triterpenoid estersaponins from the root barks of Pittosporum verticillatum subsp. verticillatum and evaluation of cytotoxicities

Cited by 21 publications

References 10 publications

Nutritional Value and Antimicrobial Activity of Pittosporum angustifolium (Gumby Gumby), an Australian Indigenous Plant

Nutritional Value and Antimicrobial Activity of Pittosporum angustifolium (Gumby Gumby), an Australian Indigenous Plant

New Caledonia: A Hot Spot for Valuable Chemodiversity Part 3: Santalales, Caryophyllales, and Asterids

Triterpenoids

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