New triterpenoid saponin glycosides from the fruit fibers ofTrichosanthes cucumerinaL.

Abstract

The new glycosides 1–5, together with eleven known compounds were isolated. Two compounds exhibited more potent anti-inflammatory activity than Celecoxib and aminoguanidine reference compounds.

Stephapierrines A–H, new tetrahydroprotoberberine and aporphine alkaloids from the tubers of Stephania pierrei Diels and their anti-cholinesterase activities

“…2 ). 50 The HMBC correlation between the methoxy proton at δ H 3.72 and a carbon resonance at δ C 147.9 (C-1) confirmed that the location of the methoxy group was placed to C-1. Additionally, the structural assignment for compound 6 was supported by the analysis of its NOESY spectrum (see Fig.…”

Anti-Acne Vulgaris Potential of the Ethanolic Extract of Mesua ferrea L. Flowers

“…Inhibition of NO Production and Pro-Inflammatory Cytokines RAW 264.7 macrophages at a density of 1.5 × 10 5 cells well −1 were treated with the test sample in the presence of LPS (1 µg mL −1 ) for 24 h. The conditioned culture media was then collected and centrifuged at 1620× g in a refrigerated centrifuge at 4 • C for 10 min. The supernatant was measured for nitrite levels by the Griess assay [29]. Optical density was measured at 550 nm.…”