New Xenicane Diterpenes Isolated from the Acetone Extract of the Soft Coral Xenia florida

Abstract

Six new xenicane diterpenes have been isolated from the acetone extract of the soft coral Xenia florida. Two of them are diterpenes containing a bicyclic [4.3.1] ring system. Three of them seem to be precursors for diterpenes possessing the bicyclic [4.3.1] ring system. One is a common monocarbocyclic diterpene with a cyclononane skeleton.

Three New Cadinene Derivatives from Xenia Puerto‐Galerae

“…1,2 These corals have been widely studied as they afford a huge number of terpenes with unique structural features and biological activity. [3][4][5][6][7] Xenia (Xeniidae) commonly occurs in clear water of the tropics in the form of small yellowish cylindrical or clavate colonies. 8 The genus has proved to be a rich source of diterpenoids containing a 9-membered monocarbocyclic ring (xenicanes) 6 as well as sesquiterpenes with cadinene skeletons.…”

Induction of Apoptosis by Diterpenes from the Soft Coral Xenia elongata

“…The 13 C NMR and HMBC data indicated two carbonyl signals: one belonged to the acetate group [δ 170.3] attached to C-3, and the other one was the carbonyl [δ 172.30, C-1] of the methyl ester moiety. The NMR data of 4 were also compared to those of xenibecin, 15 florlide F, 16 and 9-deoxyisoxeniolide-A, 17 which led to the conclusion that the structure of 4 is analogous to florlide F, 16 with the only difference in the ring system, in which one double bond appears between C-7 and C-8, similar to that found in the ring system of xenibecin and 9-deoxyisoxeniolide-A. The relative configuration at C-4a and C-11a was deduced by ROESY analysis.…”

Terpenoids from Marine Soft Coral of the Genus Xenia in 1977 to 2019

“…In 1998, seven new diterpenoids, florlides A-E (26-30) and florethers A and B (31 and 32), were isolated from X. florida collected at Bonotsu, Kagoshima Prefecture, Japan [33]. In 2000, six new diterpenoids, namely 11-O-methylflorlide A (33), 2β-epoxyfloridicin (34), xeniafaraunol B (35), and florlides F-H (36)(37)(38), were isolated from X. florida collected at Bonotsu, Kagoshima Prefecture, Japan [34]. In 2005, three new diterpenoids, xeniolactones A-C (39-41), were isolated from X. florida collected at Green Island, off Taiwan [35].…”