T he COVID-19 pandemic has highlighted the important role of state and local health departments (LHDs). Historically, LHDs have looked to state partners and states have looked to the Centers for Disease Control and Prevention (CDC) for leadership on public health management and communication efforts. However, because of the politicization of COVID-19, states and LHDs have taken very different approaches to addressing COVID-19. In some cases, LHDs have had to respond to health guidance issued from political offices before it is shared or cleared with them. In other cases, LHDs have had to scramble to address COVID-19 on their own. Staff and leadership turnover has also been an issue. 1 The public health workforce, historically understaffed and underfunded, has become strained beyond capacity, 2 making it difficult or impossible to carry out its work due to a lack of resources.At the same time, public health workers have been fighting what the World Health Organization (WHO) describes as an infodemic: "an overabundance of information, both online and offline . . . including deliberate attempts to disseminate wrong information to undermine the public health response and advance alternative agendas of groups or individuals." 3 Misinformation can impact attitudes and behaviors, 4 making it critical that LHDs respond to infodemics, including conspiracy theories, undermining their work. While the infodemic first impacted attitudes about COVID-19, it is now also influencing vaccination.