New zirconia-based materials for dental applications. Structural, morphological and histological evaluation

Bartwal

Advanced NanoBiomed Research

et al. 2021

Advancement in nanotechnology supports system development to achieve rapid, affordable, and intelligent health management and has raised the urgent demand to explore multimodel affordable metal oxide nanostructures with the features of biocompatible tunable performance and scaled‐up processing. Keeping this as a motivation, zirconia nanostructures (Zr‐NSs) are emerging as nanostructures of choice for advanced biomedical applications due to affordable, scalable production, easy surface modifications, tunable surface morphology, multiphase stability, and acceptability by biological features such as biocompatibility, viability for bioactives, and a high isoelectric point of 9.5. Zr‐NSs, alone and in the form of hybrids, and nanocomposites have demonstrated notable high performance to develop next‐generation biosensors, implanted materials, and bioelectronics. However, their excellent salient features toward high‐performance biomedical system development are not well articulated in the form of a review. To overcome this knowledge gap, herein an attempt is made to summarize state‐of‐the‐art Zr‐NS preparation techniques as per targeted applications, surface functionalization of Zr‐NSs to achieve desired properties, and applications of Zr‐NSs in the field of biomedicine for health wellness. The challenges, possible solutions, and authors’ viewpoints considering prospects in mind are also part of this report.

Section: High‐performance Biomedical Applications Of Multimodel Zr‐nssmentioning

confidence: 99%

Emerging Multimodel Zirconia Nanosystems for High‐Performance Biomedical Applications

Bartwal

Advanced NanoBiomed Research

et al. 2021

“…Zirconia is known to have three types of crystal: monoclinic ( m -ZrO 2 ), tetragonal ( t -ZrO 2 ), and cubic ( c -ZrO 2 ). The ZrO 2 phase is unstable and can undergo structural transformations such as t -ZrO 2 to m -ZrO 2 [ 9 ]. Metastable tetragonal zirconia is able to transform stress-assisted into the monoclinic state at an ambient temperature if an external load is applied [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Structural Stability, Mechanical Properties, and Corrosion Resistance of Magnesia Partially Stabilized Zirconia (Mg-PSZ)

Yusuf

Maryani²,

Mardhian

et al. 2023

Molecules

Nano Zirconia (ZrO2) has been used in dental implants due to having excellent mechanical properties and biocompatibility that match the requirements for the purpose. Zirconia undergoes phase transformation during heating: monoclinic (room temperature to 1170 °C), tetragonal (1170 °C to 2370 °C), and cubic (>2370 °C). Most useful mechanical properties can be obtained when zirconia is in a multiphase form or in partially stabilized zirconia (PSZ), which is achieved by adding small amounts of a metal oxide dopant, such as MgO (magnesia). This study aimed to synthesize nano Mg-PSZ from a local resource found in West Kalimantan, Indonesia, and examine its structural stability, biochemical stability, and mechanical properties. Nano Mg-PSZ was prepared from a zircon local to Indonesia, from West Kalimantan Province, MgSO4∙7H2O, and polyethylene glycol (PEG)-6000 was used as a template. The obtained t-ZrO2 after calcination at 800 °C was shown to be stable at room temperature. The highest percentage of the t-ZrO2 phase was obtained at Zr0.95Mg0.05O2 with a variation of 99.5%. The hardness of Mg-PSZ increased from 554 MPa for ZrO2 without MgO doping to 5266 MPa for ZrO2 with a doping of 10% MgO. An in vitro biodegradation test showed that the greater the concentration of MgO in doping the ZrO2, the greater the degradation resistance of Mg-PSZ in simulated body fluid (SBF) solution.

“…Great efforts have been made to develop alternative processes for producing 3Y-TZP ceramics that are not affected by Ltd. Alternative processes are: to use a zirconia-toughened alumina composite [7][8][9], or zirconia doped with transitions metals or other elements [10][11][12]. Another alternative process is to use coatings on the zirconia surface [13][14][15].…”

Section: Introductionmentioning

confidence: 99%

Novel process for the production of 3Y-TZP ceramics: comparison between ageing in artificial saliva and accelerated ageing

Aragón-Duarte

Bernal

Reyes‐Rojas

et al. 2020

Mater. Res. Express

The degradation of tetragonal zirconia polycrystalline (3Y-TZP) ceramics prepared by a novel film growth technique, and by sintering at 1400°C, was evaluated for one year using two processes: (i) degradation under oral conditions in artificial saliva (37°C and pH 6.8) and (ii) accelerated degradation by autoclaving at 134°C at 0.2 MPa of pressure. X-ray diffraction analysis of 3Y-TZP ceramics sintered at 1400°C showed a phase transformation (tetragonal to monoclinic) in 3Y-TZP ceramics after the fifth month in artificial saliva. After 12 months in artificial saliva, there was ∼11% of monoclinic phase present in 3Y-TZP ceramics, but only ∼2% of monoclinic phase in samples that were subjected to accelerated degradation for 5 h. No correlation was found between the level of ageing during accelerated degradation and degradation in artificial saliva. There was no degradation of 3Y-TZP ceramics prepared by a novel film growth technique, independently of the degradation method used, which suggests that this material could be used for dental prosthetics.