Newborn haemorrhagic disorders: about 30 cases

Abstract

The haemorrhagic disorders are particularly frequent in neonatal period. Their causes are varied and their knowledge is capital for their good management. Our purpose was to describe the epidemiological, diagnostic, and common causes of new-bornhaemorrhagic syndrome in paediatric emergency medical department of the Rabat Children's Hospital. We conducted a descriptive study from December 2015 to April 2016, about new-borns admitted to medical emergencies for haemorrhagic syndrome defined by bleeding, exteriorized or not, whatever its importance, severity, causes and the associated clinical and biological disorders. Between December 2015 and April 2016, we identified 30 cases of newborn haemorrhagic syndromes on 594 hospitalizations (5.05%). The sex-ratio (M/F) was 1.5. None of them received vitamin K after birth and all were breastfed. Preterm infants accounted for 10%. The presentation of haemorrhage encountered was dominated by visceral bleeding especially digestive (80%), followed by epistaxis (10%), Haematuria (7%), and skin haemorrhage (3%). Physical examination was normal in most of cases with exception (nine babies had pallor with hypotonia, three babies suffered from hypovolemic shock, respiratory distress(10%), drowsiness, poor sucking and fever. The most common cause of bleeding disorder was haemorrhagic disease of the new-born (80%), disseminated intravascular coagulation (DIC) (10%), esophagitis (6.67%) and isolated thrombocytopenia (3.33%). At the end of our study, given the high frequency of vitamin k deficiency bleeding disease despite the prophylaxis received, a strengthening of the prevention system is necessary.

Galactokinase deficiency: lessons from the GalNet registry

“…In the study population, hypoglycemia was reported in 4.3% and the presence of infection was reported in 2.0%, both comparable with the general population (5-15% and 4% respectively 24,25 ). The occurrence of bleeding diathesis and encephalopathy in our study population were 8.1% and 3.9% respectively, thus higher than in the general population (2.17-5.9% and 0.3% respectively 26,27 ). The data of this study showed that in 7 of the 47 patients (14.9%) with follow-up, cognitive, and/or motor developmental delay was reported.…”

The Transport and Outcome of Sick Outborn Neonates Admitted to a Regional and District Hospital in the Upper West Region of Ghana: A Cross-Sectional Study

“…Thus, protocols for stabilisation and direct transfers need to be explored to save time [49]. It is unfortunate that one of the children who presented with bleeding after circumcision died since the condition can be prevented by ensuring that all babies, especially those born in the community, receive vitamin K and are treated with blood transfusion if necessary, though other causes of bleeding in the newborn need to be excluded [18,50].…”

Rumor surveillance in support of minimally invasive tissue sampling for diagnosing the cause of child death in low-income countries: A qualitative study

“…Moreover, another cause of seepage could be coagulation disorder occasionally found among neonates [59]. The excessive seepage that was observed only in a few bodies after MITS could also be due to limited concentrations of coagulation proteins in the deceased [59,60]. The seepage could be interpreted as the unintended consequences of purposive social actions [39].…”