Newcastle disease: Evolution of genotypes and the related diagnostic challenges

Miller, Patti J.; Lucio-Decanini, Eduardo; Afonso, Claudio L.

doi:10.1016/j.meegid.2009.09.012

Cited by 373 publications

(397 citation statements)

References 94 publications

Supporting

Mentioning

383

Contrasting

Unclassified

Order By: Relevance

“…Newcastle disease is a global disease with a presence in six out of the seven continents [66]. In Nigeria, the disease has been detected in all the agro-ecological zones of the country (NVRI unpublished data, 2006).…”

Section: Epizootiology Of Nd In Nigeriamentioning

confidence: 99%

“…Though, this genotype has not been detected from any of our current surveillance (active and passive) activities. The existence of the genotype has been reported to have ceased to be in circulation across the globe since 1989 [66]. Genotype VI viruses are characterized by pigeon paramyxoviruses (PPMV) which are variants of NDV.…”

Section: Epizootiology Of Nd In Nigeriamentioning

confidence: 99%

“…Globally, genotype VII has been reported to be responsible for outbreaks in other countries of the world and current panzootic [66] with no report yet in West Africa. Although, the presence of the genotype has been established elsewhere in Africa, namely; Egypt [88], Libya [51], Sudan [42], South Africa [1], Mozambique [35], and Ethiopia [33].…”

Section: Epizootiology Of Nd In Nigeriamentioning

confidence: 99%

See 2 more Smart Citations

Newcastle disease in Nigeria: epizootiology and current knowledge of circulating genotypes

2016

View full text Add to dashboard Cite

Over the years, Newcastle disease (ND) has defied all available control measures. The disease has remained at the forefront of infectious diseases afflicting poultry production after avian influenza. Despite the continuous global use of million doses of ND vaccine annually, the causative pathogen, avian paramyxovirus type 1 also known as Newcastle disease virus (NDV) has continued to evolve causing, even more, a threat not only to the unvaccinated but the vaccinated flocks inclusive. The disease has been well studied in the developed countries where the virus is found in circulation. However, limited information exists on the epizootiology and circulating genotypes of the virus in developing countries where the majority of the flocks are raised on the extensive management system. Identification of virulent NDV in apparently healthy free-range ducks in this system calls for concern and pragmatic approach to investigate factor(s) that favour the virus inhabiting the ducks without clinical manifestation of the disease. Recently, novel genotypes (XIV, XVII, and XVIII) with peculiarity to West and Central African countries have been discovered and due to lack or poor surveillance system possibility of hitherto unreported genotypes are likely. This review elucidates and discusses available literature on the diversity of the circulating NDV genotypes across the West Africa countries and the epizootiology (molecular) of the disease in Nigeria with the view of identifying gaps in knowledge that can assist in the development of effective vaccines and control strategies to combat the peril of the disease.

show abstract

Section: Epizootiology Of Nd In Nigeriamentioning

confidence: 99%

Section: Epizootiology Of Nd In Nigeriamentioning

confidence: 99%

Section: Epizootiology Of Nd In Nigeriamentioning

confidence: 99%

See 1 more Smart Citation

Newcastle disease in Nigeria: epizootiology and current knowledge of circulating genotypes

2016

View full text Add to dashboard Cite

show abstract

“…Based on complete genome or the 3 0 hypervariable region of the fusion protein (F) gene sequences, NDV isolates are classified into class I Wild, feral birds and domestic birds, except ducks and pigeons, are recognized as reservoirs of NDVs, and probably contribute to the epidemiology of ND in the domesticated poultry [2]. It has been suggested that the NDVs that spill-over from wild/feral birds or other species into poultry continue to evolve as they are rapidly passaged in chickens [4,12]. Emu birds are also susceptible to many diseases including ND which infects domesticated poultry.…”

mentioning

confidence: 99%

Isolation and characterization of genotype XIII Newcastle disease virus from Emu in India

et al. 2016

View full text Add to dashboard Cite

Newcastle disease virus (NDV) infects at least 241 species of pet and free-living birds in addition to domesticated avian species. Wild, feral and domesticated birds are recognized reservoirs of NDV, and contribute to the epidemiology of NDV in the domesticated poultry. The biological and molecular characterization of velogenic NDV (vNDV) from emus is limited. In this study, 54 tissues were collected from

show abstract

“…This report points to the prevalence and circulation of genotype II virus in India. However, reports world-wide regarding the distribution of NDV indicate the circulation of multiple genotypes I to XI [29]. The repeated outbreaks of NDV in different commercial farms and reports on isolation of the virus from non chicken species of birds from India led us to hypothesize that there might be more than one genotype that is circulating in India that had not only resulted in several outbreaks but also suggests that the vaccination programmes are not optimized to deal the existing situation.…”

mentioning

confidence: 99%

Analysis of the Fusion Protein Cleavage Site of Newcastle disease virus Isolates from India Reveals Preliminary Evidence for the Existence of II, VI and VII Genotypes

et al. 2011

View full text Add to dashboard Cite

Newcastle disease virus (NDV) has been a threat to poultry industry in most of the developing countries with a wide variety of avian species being susceptible, coupled with the presence of mobile wild bird reservoirs contributing not only to the vast genomic diversity of this virus but also to the diagnostic failures. NDV of multiple genotypes (I-XI) is known to be prevalent and reported worldwide. However, there is a paucity of information on the circulating genotypes of NDV in India. This study utilized the fusion protein cleavage site (FPCS) sequence to determine the different genotypes of NDV circulating in India. Our results indicate that majority of NDV isolates from southern states of India namely, Tamil Nadu, Kerala and Karnataka were found to belong to genotype II. However, some of the strains from Tamil Nadu and most from Uttar Pradesh belong to genotype groups VI and VII. Interestingly, three isolates recovered from Tamil Nadu grouped with genotype IV viruses (namely Herts/33) which had not been hitherto reported to GenBank since 1989. This preliminary information points to the existence of multiple genotypes and also the need for efficacy studies with vaccines incorporating multiple genotypes in controlling virulent NDV (vNDV) outbreaks in India.

show abstract

Newcastle disease: Evolution of genotypes and the related diagnostic challenges

Cited by 373 publications

References 94 publications

Newcastle disease in Nigeria: epizootiology and current knowledge of circulating genotypes

Newcastle disease in Nigeria: epizootiology and current knowledge of circulating genotypes

Isolation and characterization of genotype XIII Newcastle disease virus from Emu in India

Analysis of the Fusion Protein Cleavage Site of Newcastle disease virus Isolates from India Reveals Preliminary Evidence for the Existence of II, VI and VII Genotypes

Contact Info

Product

Resources

About