Ni(II)‐Mediated Ortho C(sp2)‐H Amidation of Arenes to Synthesis Secondary Sulfonamides via Sulfonyl Azides

Abstract

In this paper, we described Ni(II)-mediated C(sp 2 )À H amidation of arenes directed by an amide-tethered oxazoline directing group. The method provides a direct easy manner to achieve sulfonamides derivatives by available sulfonyl azides as amine source. The protocol exhibited moderate yields and functional group compatibility. Additionally, Synthetic amide compound has the Aggregation-Induced Emission (AIE) phenomenon, which exhibit the potential application in OLEDs field.

Ni‐Catalyzed/mediated C−X (X=N, O, S) Bond Formation Chelation‐Assisted by Bidentate Directing Groups

“…Next, our group [56] utilized amide‐tethered oxazoline as directing group and available sulfonyl azides as amine source to realize the amination reaction of ortho ‐C−H bond of benzamide catalyzed by nickel salts (Scheme 3b). Additionally, we have found the Aggregation‐Induced Emission (AIE) phenomenon of amide compounds, which exhibits the potential application in OLEDs field.…”