During my master's thesis, which covered the essentials of Wi-Fi location estimation, I came in contact with the concepts of indoor localization, and multi sensor fusion. Having attracted my interest, I hereafter joined the Faculty of Computer Science and Business Information Systems at the University of Applied Sciences Würzburg-Schweinfurt as a research assistant. During that time I conducted the majority of my research on indoor localization and navigation, which finally lead to writing this work.I would like to thank my colleagues during that time, but especially my local doctoral adviser Prof. Dr. Frank Deinzer. Not only did he guide me towards earning a doctors degree, he also provided extensive feedback to all publications, always ensuring utmost scientific quality. I would also like to thank my external doctoral adviser and first referee Prof. Dr. habil. Marcin Grzegorzek for his trust, all provided feedback, and the warm welcome within his research group. I also owe gratitude to my co-workers Lukas, Toni, and Markus. Without hours of mutual feedback, technical input, paired programming, data acquisition, and networking, this work would not have been possible. Likewise, I also wish to thank Prof. Dr. Karsten Huffstadt and Prof. Dr. Arndt Balzer for helping with funding my initial employment.In order to develop a generic indoor localization and navigation solution, the presented system was deployed to and tested within several unique buildings. For this, special thanks go to Dr. Hellmuth Möhring from the RothenburgMuseum in Rothenburg ob der Tauber, Prof. Dr. Günther Moosbauer from the Gäubodenmuseum in Straubing, Angelika Schreiber from the Hutmuseum in Lindenberg, the Landesstelle für die nichtstaatlichen Museen in Bayern, and the Sparkassenstiftung. By providing access and enabling temporal hardware installations they allowed gathering data within a range of unique and representative public buildings, enhancing the quality of the developed system, and the experiments provided within this work.Thanks also go to Markus, Christin, Alexander, and Maximilian, not only for spending numerous hours of their spare time with proof reading and feedback, but also for all emotional support while conducting my research and writing this work. The same goes to my parents, for always supporting me, and my education.To Katharina, who has been a true friend, and will never be forgotten.