Nickel complexes of the different quinolone antibacterial drugs: Synthesis, structure and interaction with DNA

Thermal, spectroscopic and antimicrobial activity characterization of some norfloxacin complexes

“…This band is shifted to lower frequencies in the spectra of the complexes, suggesting that this group also participates in coordination. In this way, the spectroscopic results suggest that the ligand coordinates to the metal centers by one oxygen atom from the carboxylate and one from carbonyl of ketone group, resulting in a sixmembered ring chelate, in agreement with several works found in the literature [9,13,17,29].…”

A mononuclear Ni(II) complex with 5,6-diphenyl-3-(2-pyridyl)-1,2,4-triazine: DNA- and BSA-binding and anticancer activity against human breast carcinoma cells

“…2, with the gradual addition of the complex to the DNA solution, the absorption intensity of this band increases (hyperchromism) without any obvious change in its position. This observation exhibits that the interaction between the Ni(II) complex and DNA may have caused a slight change in the conformation of DNA [31]. The plot of 1/(A À A 0 ) (where A 0 is the initial absorbance of the free DNA at 260 nm, and A is the absorbance of DNA in the presence of different concentrations of the complex) vs. 1/[complex] is a linear line, and the binding constant (K b ) can be obtained from the ratio of the intercept to slope (Fig.…”

A mononuclear Cu(II) complex with 5,6-diphenyl-3-(2-pyridyl)-1,2,4-triazine: Synthesis, crystal structure, DNA- and BSA-binding, molecular modeling, and anticancer activity against MCF-7, A-549, and HT-29 cell lines

“…The increasing of the absorption intensity at λ max = 259 nm is due to the fact that the purine and pyrimidine bases of DNA because of the binding of the complex are exposed. This observation exhibits that the interaction between the Cu(II) complex and DNA may have caused a slight change in the conformation of DNA[54]. The plot of 1/(A -A 0 ) (where A 0 is absorbance of the free DNA at 260 nm, and A is the absorbance of DNA in the presence of different concentrations of the complex) vs. 1/[Cu(II) complex] is a linear line, and the binding constant (K b ) can be obtained from the ratio of the intercept to the slope(Fig.…”