In this in vitro study, we tested 10 types of springs from 5 manufacturers. We performed a simulation of the clinically relevant action of the spring during its application and treatment of the patient. For determining the deactivation plateau, we developed an innovative statistical method, making it feasible to precisely find and evaluate the necessary clinically relevant parameters of all types of NiTi SE closed-coil springs in the market. In terms of the application simplicity, the 3M 12 and 3M 9 springs proved to be the most suitable.