NiCl(OH) nanosheet array as a high sensitivity electrochemical sensor for detecting glucose in human serum and saliva

Wang, Qiang; Wang, Zhipeng; Dong, Qiaoyan; Yu, Ruoxi; Zhu, Haihong; Zou, Zhirong; Yu, Huimin; Huang, Ke; Jiang, Xue; Xiong, Xiaoli

doi:10.1016/j.microc.2020.105184

Cited by 22 publications

(7 citation statements)

References 56 publications

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“…8−11 Although the enzymatic sensor is highly selective toward glucose molecules, its performance is easily degraded because of environmental changes, such as pH, temperature, and humidity variations. 12,13 Therefore, enzymatic glucose sensors are not suitable for wearable continuous glucose monitoring systems. Significant efforts have been devoted to developing non-enzymatic glucose sensors based on transition metals (Au, Pt, Cu, and Ni) and their transition metal oxides.…”

Section: ■ Introductionmentioning

confidence: 99%

“…Currently, the most common approach of detecting blood glucose is invasive blood sampling for glucose detection, which may cause infection and pain to people . Owing to the good correlation between glucose in blood and sweat, many non-invasive electrochemical wearable sensors of sweat glucose have been developed to replace invasive sensors of blood glucose. − However, most of these glucose sensors employ an enzymatic catalyst to detect glucose. − Although the enzymatic sensor is highly selective toward glucose molecules, its performance is easily degraded because of environmental changes, such as pH, temperature, and humidity variations. , Therefore, enzymatic glucose sensors are not suitable for wearable continuous glucose monitoring systems. Significant efforts have been devoted to developing non-enzymatic glucose sensors based on transition metals (Au, Pt, Cu, and Ni) and their transition metal oxides. − To obtain excellent performance, these sensors are generally operated under alkaline conditions (pH > 11) .…”

Section: Introductionmentioning

confidence: 99%

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Pt/MXene-Based Flexible Wearable Non-Enzymatic Electrochemical Sensor for Continuous Glucose Detection in Sweat

Chen

Wang

et al. 2023

ACS Appl. Mater. Interfaces

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Wearable non-invasive sensors facilitate the continuous measurement of glucose in sweat for the treatment and management of diabetes. However, the catalysis of glucose and sweat sampling are challenges in the development of efficient wearable glucose sensors. Herein, we report a flexible wearable non-enzymatic electrochemical sensor for continuous glucose detection in sweat. We synthesized a catalyst (Pt/MXene) by the hybridization of Pt nanoparticles onto MXene (Ti3C2T x ) nanosheets with a broad linear range of glucose detection (0–8 mmol/L) under neutral conditions. Furthermore, we optimized the structure of the sensor by immobilizing Pt/MXene with a conductive hydrogel to enhance the stability of the sensor. Based on Pt/MXene and the optimized structure, we fabricated a flexible wearable glucose sensor by integrating a microfluidic patch for sweat collection onto a flexible sensor. We evaluated the utility of the sensor for the detection of glucose in sweat, and the sensor could detect the glucose change with the replenishment and consumption of energy by the body, and a similar trend was observed in the blood. An in vivo glucose test in sweat indicated that the fabricated sensor is promising for the continuous measurement of glucose, which is essential for the treatment and management of diabetes.

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Section: ■ Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Pt/MXene-Based Flexible Wearable Non-Enzymatic Electrochemical Sensor for Continuous Glucose Detection in Sweat

Chen

Wang

et al. 2023

ACS Appl. Mater. Interfaces

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“…Hence, increasing attention has been paid to non-enzymatic electrochemical glucose determination [5][6][7][8][9][10]. As a kind of promising candidates, transition metal compounds have received tremendous attention [11][12][13][14][15][16].…”

Section: Introductionmentioning

confidence: 99%

MOF-derived NiCo hydroxide for highly efficient non-enzymatic glucose biosensing

Sun,

Sun

2024

Nanotechnology

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An efficient and robust electrocatalyst is significant for glucose biosensing. The emergence of metal-organic framework (MOF) derived materials opens up new avenues for the development of high-performance glucose sensing catalysts. Herein, MOF derived nickel-cobalt hydroxide supported on conductive copper sheet (NiCo-OH/Cu sheet) is prepared at room temperature. The as-obtained NiCo-OH is endowed with three-dimensional network structure which enables the effective exposure of active materials, sufficient contact between glucose molecule and catalyst. The NiCo-OH/Cu sheet is revealed as good glucose electrochemical sensing material with a wide linear range of 0.05~6.0 mM and a high sensitivity of 1340 μA mM-1 cm-2. Additionally, the as-fabricated NiCo-OH/Cu sheet displays good anti-interference ability and long-term stability.

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“…In our previous work, we synthesized nickel-based nanorods and nanosheets by a flame method, hydrothermal method, etc., that resulted in better sensing performance. However, the sensitivity, linear range, and synthesis time needed to be further optimized. − Therefore, we synthesized a cobalt-based nanosheet material rich in defects by chemical etching with defect engineering technology. Such materials are very attractive in the field of electrochemical sensing.…”

Section: Introductionmentioning

confidence: 99%

Co-Based Transition Metal Hydroxide Nanosheet Arrays on Carbon Cloth for Sensing Glucose and Formaldehyde

Dong

et al. 2021

ACS Appl. Nano Mater.

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Defect engineering has become an effective way to improve the surface performance of nanoelectrochemical catalysts. In this article, the ultrathin defect-rich Co(OH) 2 nanosheet arrays in situ grew on carbon cloth (U-D-Co(OH) 2 NSA/CC), which was synthesized by etching a metal−organic framework at room temperature. The physical and chemical properties of the obtained U-D-Co(OH) 2 NSA were characterized by X-ray diffraction, transmission electron microscopy, and X-ray photoelectron spectroscopy. It is an efficient electrode for detecting glucose and formaldehyde under alkaline conditions. As a glucose and formaldehyde sensor, it exhibited superior electrocatalytic activity, for instance, shorter response time (<5 s), limit of detection (LOD) of 0.32 μM and 0.57 μM (S/N = 3), and response sensitivity of 6759.0 μA mM −1 cm −2 for glucose and 2444.0 μA mM −1 cm −2 for formaldehyde with outstanding reproducibility and selectivity, respectively.

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NiCl(OH) nanosheet array as a high sensitivity electrochemical sensor for detecting glucose in human serum and saliva

Cited by 22 publications

References 56 publications

Pt/MXene-Based Flexible Wearable Non-Enzymatic Electrochemical Sensor for Continuous Glucose Detection in Sweat

Pt/MXene-Based Flexible Wearable Non-Enzymatic Electrochemical Sensor for Continuous Glucose Detection in Sweat

MOF-derived NiCo hydroxide for highly efficient non-enzymatic glucose biosensing

Co-Based Transition Metal Hydroxide Nanosheet Arrays on Carbon Cloth for Sensing Glucose and Formaldehyde

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